ENSDARG00000043587


Danio rerio

Features
Gene ID: ENSDARG00000043587
  
Biological name :srd5a2a
  
Synonyms : srd5a2a / steroid-5-alpha-reductase, alpha polypeptide 2a
  
Possible biological names infered from orthology : 3-oxo-5-alpha-steroid 4-dehydrogenase 2 / P31213 / Q99N99 / SRD5A2 / steroid 5 alpha-reductase 2
  
Species: Danio rerio
  
Chr. number: 1
Strand: 1
Band:
Gene start: 51066671
Gene end: 51073128
  
Corresponding Affymetrix probe sets: Dr.9952.1.A1_at (Zebrafish Array)   Dr.9952.2.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000064006
Ensembl peptide - ENSDARP00000110065
NCBI entrez gene - 550398     See in Manteia.
swissprot - E9QHW4
swissprot - Q566Z4
ZFIN ID - ZDB-GENE-050417-199
Ensembl - ENSDARG00000043587
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SRD5A2ENSGALG00000010625Gallus gallus
 P31213ENSG00000277893Homo sapiens
 Q99N99ENSMUSG00000038541Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
srd5a2b / steroid-5-alpha-reductase, alpha polypeptide 2b / SRD5A2* / P31213* / Q99N99* / steroid 5 alpha-reductase 2* / 3-oxo-5-alpha-steroid 4-dehydrogenase 2 *ENSDARG0000003906755
srd5a1 / steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) / P18405* / steroid 5 alpha-reductase 1*ENSDARG0000002050946


Protein motifs (from Interpro)
Interpro ID Name
 IPR001104  3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal
 IPR016636  3-oxo-5-alpha-steroid 4-dehydrogenase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006694 steroid biosynthetic process IBA
 biological_processGO:0008202 steroid metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity IBA
 molecular_functionGO:0016627 oxidoreductase activity, acting on the CH-CH group of donors IEA


Pathways (from Reactome)
Pathway description
Androgen biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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