ENSDARG00000043665


Danio rerio

Features
Gene ID: ENSDARG00000043665
  
Biological name :glrx5
  
Synonyms : glrx5 / glutaredoxin 5 homolog (S. cerevisiae) / Q6PBM1
  
Possible biological names infered from orthology : glutaredoxin 5 / Glutaredoxin-related protein 5, mitochondrial / Q80Y14 / Q86SX6
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 10484015
Gene end: 10487951
  
Corresponding Affymetrix probe sets: Dr.311.1.S1_at (Zebrafish Array)   NM_213021_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000064111
NCBI entrez gene - 406294     See in Manteia.
RefSeq - NM_213021
RefSeq Peptide - NP_998186
swissprot - Q6PBM1
ZFIN ID - ZDB-GENE-040426-1957
Ensembl - ENSDARG00000043665
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GLRX5ENSGALG00000011079Gallus gallus
 GLRX5ENSG00000182512Homo sapiens
 Glrx5ENSMUSG00000021102Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002109  Glutaredoxin
 IPR004480  Monothiol glutaredoxin-related
 IPR012336  Thioredoxin-like fold
 IPR014434  Monothiol glutaredoxin
 IPR033658  Glutaredoxin, PICOT-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016226 iron-sulfur cluster assembly IMP
 biological_processGO:0022900 electron transport chain IEA
 biological_processGO:0030097 hemopoiesis IMP
 biological_processGO:0045454 cell redox homeostasis IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005739 mitochondrion IDA
 molecular_functionGO:0009055 electron transfer activity IEA
 molecular_functionGO:0015035 protein disulfide oxidoreductase activity IEA
 molecular_functionGO:0015036 disulfide oxidoreductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051536 iron-sulfur cluster binding IEA
 molecular_functionGO:0051537 2 iron, 2 sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
Mitochondrial iron-sulfur cluster biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000007 blood blood quality , abnormal
Show

 ZFA:0001094 whole organism whole organism viability , abnormal
Show

 ZFA:0009044 blood cell blood cell low saturation , abnormal
Show

 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte decreased amount , abnormal
nucleate erythrocyte low saturation , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000043665 glrx5 / Q6PBM1 / glutaredoxin 5 homolog (S. cerevisiae) / Q86SX6* / Q80Y14* / glutaredoxin 5* / Glutaredoxin-related protein 5, mitochondrial *  / reaction
 ENSDARG00000051956 isca1 / Q4QRC6 / iron-sulfur cluster assembly 1 / Q9BUE6*  / reaction






 

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