ENSDARG00000045219


Danio rerio

Features
Gene ID: ENSDARG00000045219
  
Biological name :dkk1b
  
Synonyms : dickkopf WNT signaling pathway inhibitor 1b / dkk1b
  
Possible biological names infered from orthology : Dickkopf-related protein 1 / dickkopf WNT signaling pathway inhibitor 1 / DKK1 / O54908 / O94907
  
Species: Danio rerio
  
Chr. number: 12
Strand: 1
Band:
Gene start: 6465557
Gene end: 6467675
  
Corresponding Affymetrix probe sets: Dr.8056.1.S1_at (Zebrafish Array)   NM_131003_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000066476
Ensembl peptide - ENSDARP00000112296
NCBI entrez gene - 30197     See in Manteia.
RefSeq - NM_131003
RefSeq - XM_005172963
RefSeq Peptide - NP_571078
swissprot - Q9PWH3
swissprot - F1QAX3
ZFIN ID - ZDB-GENE-990708-5
Ensembl - ENSDARG00000045219
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DKK1ENSGALG00000003814Gallus gallus
 DKK1ENSG00000107984Homo sapiens
 Dkk1ENSMUSG00000024868Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dkk1a / dickkopf WNT signaling pathway inhibitor 1a / DKK1* / O94907* / O54908* / Dickkopf-related protein 1 * / dickkopf WNT signaling pathway inhibitor 1*ENSDARG0000001410345
dkk2 / dickkopf WNT signaling pathway inhibitor 2 / Q9QYZ8* / Q9UBU2* / Dickkopf-related protein 2 *ENSDARG0000007642037


Protein motifs (from Interpro)
Interpro ID Name
 IPR006796  Dickkopf, N-terminal cysteine-rich


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001889 liver development IGI
 biological_processGO:0003197 endocardial cushion development IMP
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007398 ectoderm development IGI
 biological_processGO:0021879 forebrain neuron differentiation IMP
 biological_processGO:0030178 negative regulation of Wnt signaling pathway IGI
 biological_processGO:0030334 regulation of cell migration IGI
 biological_processGO:0030900 forebrain development IGI
 biological_processGO:0030903 notochord development IGI
 biological_processGO:0042074 cell migration involved in gastrulation IMP
 biological_processGO:0043697 cell dedifferentiation IGI
 biological_processGO:0048919 posterior lateral line neuromast development IMP
 biological_processGO:0061011 hepatic duct development IGI
 biological_processGO:0070654 sensory epithelium regeneration IGI
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IGI
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005737 cytoplasm IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary increased width , abnormal
Show

 ZFA:0000079 telencephalon telencephalon decreased size , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
eye absent , abnormal
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 ZFA:0000155 somite somite increased width , abnormal
somite condensed , abnormal
Show

 ZFA:0001064 rhombomere rhombomere increased width , abnormal
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 ZFA:0001114 head head truncated , abnormal
Show

 ZFA:0001306 pharyngeal arch pharyngeal arch morphology , abnormal
pharyngeal arch decreased size , abnormal
pharyngeal arch malformed , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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