ENSGALG00000003814


Gallus gallus

Features
Gene ID: ENSGALG00000003814
  
Biological name :DKK1
  
Synonyms : dickkopf WNT signaling pathway inhibitor 1 / DKK1
  
Possible biological names infered from orthology : Dickkopf-related protein 1 / O54908 / O94907
  
Species: Gallus gallus
  
Chr. number: 6
Strand: 1
Band:
Gene start: 10258629
Gene end: 10260345
  
Corresponding Affymetrix probe sets: Gga.897.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000006037
swissprot - F6ULT8
Ensembl - ENSGALG00000003814
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dkk1aENSDARG00000014103Danio rerio
 dkk1bENSDARG00000045219Danio rerio
 DKK1ENSG00000107984Homo sapiens
 Dkk1ENSMUSG00000024868Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DKK2 / dickkopf WNT signaling pathway inhibitor 2 / Q9QYZ8* / Q9UBU2* / Dickkopf-related protein 2 *ENSGALG0000002804145


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0000904 cell morphogenesis involved in differentiation IEA
 biological_processGO:0001706 endoderm formation IEA
 biological_processGO:0001707 mesoderm formation IEA
 biological_processGO:0001942 hair follicle development IEA
 biological_processGO:0002090 regulation of receptor internalization IEA
 biological_processGO:0007492 endoderm development IEA
 biological_processGO:0007611 learning or memory IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0030111 regulation of Wnt signaling pathway IEA
 biological_processGO:0030178 negative regulation of Wnt signaling pathway IEA
 biological_processGO:0030279 negative regulation of ossification IEA
 biological_processGO:0030326 embryonic limb morphogenesis IEA
 biological_processGO:0030514 negative regulation of BMP signaling pathway IEA
 biological_processGO:0030900 forebrain development IEA
 biological_processGO:0032091 negative regulation of protein binding IEA
 biological_processGO:0032526 response to retinoic acid IEA
 biological_processGO:0033137 negative regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0042662 negative regulation of mesodermal cell fate specification IEA
 biological_processGO:0042663 regulation of endodermal cell fate specification IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043507 positive regulation of JUN kinase activity IEA
 biological_processGO:0048642 negative regulation of skeletal muscle tissue development IEA
 biological_processGO:0050807 regulation of synapse organization IEA
 biological_processGO:0051966 regulation of synaptic transmission, glutamatergic IEA
 biological_processGO:0060173 limb development IEA
 biological_processGO:0060323 head morphogenesis IEA
 biological_processGO:0060325 face morphogenesis IEA
 biological_processGO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation IEA
 biological_processGO:0061743 motor learning IEA
 biological_processGO:0090082 positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway IEA
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IEA
 biological_processGO:0090244 Wnt signaling pathway involved in somitogenesis IEA
 biological_processGO:0090647 modulation of age-related behavioral decline IEA
 biological_processGO:1900116 extracellular negative regulation of signal transduction IEA
 biological_processGO:1901296 negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment IEA
 biological_processGO:1902949 positive regulation of tau-protein kinase activity IEA
 biological_processGO:1904723 negative regulation of Wnt-Frizzled-LRP5/6 complex assembly IEA
 biological_processGO:1904958 positive regulation of midbrain dopaminergic neuron differentiation IEA
 biological_processGO:2000726 negative regulation of cardiac muscle cell differentiation IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005886 plasma membrane IEA
 molecular_functionGO:0039706 co-receptor binding IEA
 molecular_functionGO:0048019 receptor antagonist activity IEA
 molecular_functionGO:0050750 low-density lipoprotein particle receptor binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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