ENSDARG00000051939


Danio rerio

Features
Gene ID: ENSDARG00000051939
  
Biological name :pcxb
  
Synonyms : pcxb / pyruvate carboxylase b
  
Possible biological names infered from orthology : P11498 / PC / Pcx / pyruvate carboxylase
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 60457138
Gene end: 60831105
  
Corresponding Affymetrix probe sets: Dr.5402.1.A1_at (Zebrafish Array)   Dr.5998.1.S1_at (Zebrafish Array)   NM_131550_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000068144
Ensembl peptide - ENSDARP00000123254
NCBI entrez gene - 58068     See in Manteia.
RefSeq - NM_131550
RefSeq Peptide - NP_571625
swissprot - F1QYZ6
swissprot - B0S5R6
ZFIN ID - ZDB-GENE-000831-1
Ensembl - ENSDARG00000051939
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PCENSG00000173599Homo sapiens
 PcxENSMUSG00000024892Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pcxa / pyruvate carboxylase a / PC* / Pcx* / P11498* / pyruvate carboxylase*ENSDARG0000009876690


Protein motifs (from Interpro)
Interpro ID Name
 IPR000089  Biotin/lipoyl attachment
 IPR000891  Pyruvate carboxyltransferase
 IPR001882  Biotin-binding site
 IPR003379  Carboxylase, conserved domain
 IPR005479  Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain
 IPR005481  Biotin carboxylase-like, N-terminal domain
 IPR005482  Biotin carboxylase, C-terminal
 IPR005930  Pyruvate carboxylase
 IPR011053  Single hybrid motif
 IPR011054  Rudiment single hybrid motif
 IPR011761  ATP-grasp fold
 IPR011764  Biotin carboxylation domain
 IPR013785  Aldolase-type TIM barrel
 IPR013815  ATP-grasp fold, subdomain 1
 IPR016185  Pre-ATP-grasp domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006090 pyruvate metabolic process IEA
 biological_processGO:0006094 gluconeogenesis IEA
 biological_processGO:0046686 response to cadmium ion IEP
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004736 pyruvate carboxylase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0009374 biotin binding IEA
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Biotin transport and metabolism
Gluconeogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000051939 pcxb / pyruvate carboxylase b / PC* / Pcx* / P11498* / pyruvate carboxylase*  / complex
 ENSDARG00000098766 pcxa / pyruvate carboxylase a / PC* / Pcx* / P11498* / pyruvate carboxylase*  / complex






 

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