ENSDARG00000052122


Danio rerio

Features
Gene ID: ENSDARG00000052122
  
Biological name :rag1
  
Synonyms : rag1 / recombination activating gene 1
  
Possible biological names infered from orthology : P15918 / P15919 / recombination activating 1 / V(D)J recombination-activating protein 1 Endonuclease RAG1 E3 ubiquitin-protein ligase RAG1
  
Species: Danio rerio
  
Chr. number: 25
Strand: 1
Band:
Gene start: 9003230
Gene end: 9009902
  
Corresponding Affymetrix probe sets: Dr.5748.1.S1_at (Zebrafish Array)   NM_131389_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000120100
Ensembl peptide - ENSDARP00000145989
Ensembl peptide - ENSDARP00000149705
Ensembl peptide - ENSDARP00000150596
NCBI entrez gene - 30663     See in Manteia.
RefSeq - XM_005162976
RefSeq - NM_131389
RefSeq - XM_009297786
RefSeq Peptide - NP_571464
swissprot - F1QD74
ZFIN ID - ZDB-GENE-990415-234
Ensembl - ENSDARG00000052122
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RAG1ENSGALG00000007938Gallus gallus
 RAG1ENSG00000166349Homo sapiens
 Rag1ENSMUSG00000061311Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site
 IPR018957  Zinc finger, C3HC4 RING-type
 IPR019485  V(D)J recombination-activating protein 1, Zinc finger
 IPR023336  RAG nonamer-binding domain
 IPR024627  V(D)J recombination-activating protein 1
 IPR035714  RAG1 importin-binding


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006310 DNA recombination IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0033151 V(D)J recombination IEA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0004519 endonuclease activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000037 anatomical structure anatomical structure decreased amount , abnormal
anatomical structure amount , ameliorated
anatomical structure increased amount , abnormal
Show

 ZFA:0000108 fin fin morphology , abnormal
Show

 ZFA:0000112 gut gut increased amount , abnormal
Show

 ZFA:0000123 liver liver increased amount , abnormal
Show

 ZFA:0000368 integument integument increased amount , abnormal
integument leukocyte increased amount , abnormal
Show

 ZFA:0000529 kidney kidney increased amount , abnormal
kidney decreased amount , abnormal
Show

 ZFA:0000669 head kidney head kidney T cell absent , abnormal
head kidney B cell absent , abnormal
head kidney increased amount , abnormal
Show

 ZFA:0001094 whole organism whole organism viability , abnormal
whole organism decreased size , abnormal
whole organism decreased life span , abnormal
whole organism decreased life span , ameliorated
Show

 ZFA:0005145 muscle muscle leukocyte increased amount , abnormal
Show

 ZFA:0009048 granulocyte granulocyte increased amount , abnormal
Show

 ZFA:0009250 lymphocyte lymphocyte decreased amount , abnormal
lymphocyte absent , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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