ENSDARG00000052674


Danio rerio

Features
Gene ID: ENSDARG00000052674
  
Biological name :csnk1a1
  
Synonyms : casein kinase 1, alpha 1 / csnk1a1
  
Possible biological names infered from orthology : casein kinase 1 alpha 1 like / CSNK1A1L / P48729 / Q8BK63 / Q8N752
  
Species: Danio rerio
  
Chr. number: 14
Strand: -1
Band:
Gene start: 38762977
Gene end: 38783619
  
Corresponding Affymetrix probe sets: Dr.18561.3.S1_a_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000142599
Ensembl peptide - ENSDARP00000104911
Ensembl peptide - ENSDARP00000107253
Ensembl peptide - ENSDARP00000130178
Ensembl peptide - ENSDARP00000142150
NCBI entrez gene - 192307     See in Manteia.
RefSeq - NM_152951
RefSeq Peptide - NP_694483
swissprot - Q8JG73
swissprot - A0A140LFX4
swissprot - Q8JHD9
swissprot - Q8JHE0
swissprot - Q8JGT0
ZFIN ID - ZDB-GENE-020419-19
Ensembl - ENSDARG00000052674
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P67962ENSGALG00000001364Gallus gallus
 P48729ENSG00000113712Homo sapiens
 Q8N752ENSG00000180138Homo sapiens
 Q8BK63ENSMUSG00000024576Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
csnk1e / casein kinase 1, epsilon / P49674* / Q9JMK2* / Z98749.3* / Casein kinase I isoform epsilon *ENSDARG0000004515063
Q6P3K7 / csnk1db / casein kinase 1, delta b / Q9DC28* / CSNK1D* / P48730* / casein kinase 1 delta*ENSDARG0000000612563
Q7T2E3 / csnk1da / casein kinase 1, delta a / CSNK1D* / P48730* / casein kinase 1 delta*ENSDARG0000000837063
ttbk1b / tau tubulin kinase 1b / TTBK1* / Q5TCY1* / Q6PCN3* / tau tubulin kinase 1*ENSDARG0000005665930
ttbk2a / tau tubulin kinase 2a / TTBK2* / Q3UVR3* / Q6IQ55* / tau tubulin kinase 2*ENSDARG0000000567030
ttbk1a / tau tubulin kinase 1a / TTBK1* / Q5TCY1* / Q6PCN3* / tau tubulin kinase 1*ENSDARG0000005601929
ttbk2b / tau tubulin kinase 2b / TTBK2* / Q3UVR3* / Q6IQ55* / tau tubulin kinase 2*ENSDARG0000004302627


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0006909 phagocytosis IBA
 biological_processGO:0007507 heart development IMP
 biological_processGO:0008360 regulation of cell shape IBA
 biological_processGO:0016055 Wnt signaling pathway IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IDA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IDA
 molecular_functionGO:0005524 ATP binding IC
 molecular_functionGO:0016301 kinase activity IEA


Pathways (from Reactome)
Pathway description
Degradation of beta-catenin by the destruction complex
Beta-catenin phosphorylation cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000009 cardiac ventricle cardiac ventricle dilated , abnormal
Show

 ZFA:0000059 postoptic commissure postoptic commissure morphology , abnormal
postoptic commissure astrocyte mislocalised , abnormal
Show

 ZFA:0000095 pharyngeal arch 3-7 skeleton pharyngeal arch 3-7 skeleton quality , abnormal
Show

 ZFA:0000109 forebrain forebrain commissural neuron axon guidance disrupted , abnormal
forebrain astrocyte morphology , abnormal
Show

 ZFA:0000292 surface structure surface structure quality , abnormal
Show

 ZFA:0000435 cranial nerve II cranial nerve II defasciculated , abnormal
Show

 ZFA:0000471 atrium atrium dilated , abnormal
Show

 ZFA:0001108 anterior commissure anterior commissure morphology , abnormal
anterior commissure astrocyte mislocalised , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
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 ZFA:0001161 pectoral fin pectoral fin shape , abnormal
pectoral fin stubby , abnormal
pectoral fin quality , abnormal
Show

 ZFA:0001205 Meckel s cartilage Meckels cartilage decreased length , abnormal
Show

 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton shape , abnormal
mandibular arch skeleton decreased size , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage morphology , abnormal
Show

 ZFA:0001501 cartilage element cartilage element wrinkled , abnormal
cartilage element decreased length , abnormal
cartilage element rough , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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