ENSGALG00000001364


Gallus gallus

Features
Gene ID: ENSGALG00000001364
  
Biological name :CSNK1A1
  
Synonyms : Casein kinase I isoform alpha / CSNK1A1 / P67962
  
Possible biological names infered from orthology : casein kinase 1 alpha 1 / casein kinase 1 alpha 1 like / CSNK1A1L / P48729 / Q8BK63 / Q8N752
  
Species: Gallus gallus
  
Chr. number: 13
Strand: 1
Band:
Gene start: 8450253
Gene end: 8481381
  
Corresponding Affymetrix probe sets: Gga.3287.1.S1_a_at (Chicken Array)   Gga.3287.2.S2_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000002080
Ensembl peptide - ENSGALP00000040233
NCBI entrez gene - 395924     See in Manteia.
RefSeq - XM_015293674
RefSeq - NM_205053
RefSeq - XM_015293671
RefSeq - XM_015293672
RefSeq - XM_015293673
RefSeq Peptide - NP_990384
swissprot - F1NNY1
swissprot - F1NL64
swissprot - P67962
Ensembl - ENSGALG00000001364
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 csnk1a1ENSDARG00000052674Danio rerio
 P48729ENSG00000113712Homo sapiens
 Q8N752ENSG00000180138Homo sapiens
 Q8BK63ENSMUSG00000024576Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CSNK1E / Q5ZLL1 / Casein kinase I isoform epsilon / Q9JMK2* / P49674* / Z98749.3* / casein kinase 1 epsilon*ENSGALG0000003225765
CSNK1D / casein kinase 1 delta / P48730* / Q9DC28*ENSGALG0000000271964
TTBK1 / tau tubulin kinase 1 / Q5TCY1* / Q6PCN3*ENSGALG0000000862731
TTBK2 / tau tubulin kinase 2 / Q3UVR3* / Q6IQ55*ENSGALG0000000917627


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000902 cell morphogenesis IEA
 biological_processGO:0006468 protein phosphorylation ISS
 biological_processGO:0006909 phagocytosis IBA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0008360 regulation of cell shape IBA
 biological_processGO:0016055 Wnt signaling pathway IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0045104 intermediate filament cytoskeleton organization ISS
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005847 mRNA cleavage and polyadenylation specificity factor complex ISS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0016607 nuclear speck ISS
 cellular_componentGO:0036064 ciliary basal body ISS
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0045095 keratin filament ISS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Degradation of beta-catenin by the destruction complex
Beta-catenin phosphorylation cascade
Disassembly of the destruction complex and recruitment of AXIN to the membrane
GLI3 is processed to GLI3R by the proteasome
Activation of SMO


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000040266 GLI3 / GLI family zinc finger 3 / P10071* / Q61602* / Transcriptional activator GLI3 Transcriptional repressor GLI3R*  / reaction
 ENSGALG00000008096 SUFU / SUFU negative regulator of hedgehog signaling / Q9UMX1* / Q9Z0P7*  / reaction
 ENSGALG00000036114 SMO / smoothened, frizzled class receptor / P56726* / Q99835*  / complex






 

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