ENSGALG00000032257


Gallus gallus

Features
Gene ID: ENSGALG00000032257
  
Biological name :CSNK1E
  
Synonyms : Casein kinase I isoform epsilon / CSNK1E / Q5ZLL1
  
Possible biological names infered from orthology : casein kinase 1 epsilon / P49674 / Q9JMK2 / Z98749.3
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 50962355
Gene end: 50982806
  
Corresponding Affymetrix probe sets: Gga.2087.1.S1_s_at (Chicken Array)   Gga.2087.1.S2_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000064070
Ensembl peptide - ENSGALP00000053098
NCBI entrez gene - 378891     See in Manteia.
RefSeq - NM_204377
RefSeq Peptide - NP_989708
swissprot - Q5ZLL1
swissprot - A0A1L1RYX4
Ensembl - ENSGALG00000032257
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 csnk1eENSDARG00000045150Danio rerio
 CSNK1EENSG00000213923Homo sapiens
 Z98749.3ENSG00000283900Homo sapiens
 Csnk1eENSMUSG00000022433Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CSNK1D / casein kinase 1 delta / P48730* / Q9DC28*ENSGALG0000000271984
P67962 / CSNK1A1 / Casein kinase I isoform alpha / Q8N752* / P48729* / Q8BK63* / CSNK1A1L* / casein kinase 1 alpha 1* / casein kinase 1 alpha 1 like*ENSGALG0000000136455
TTBK1 / tau tubulin kinase 1 / Q5TCY1* / Q6PCN3*ENSGALG0000000862730
TTBK2 / tau tubulin kinase 2 / Q3UVR3* / Q6IQ55*ENSGALG0000000917622


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006897 endocytosis IBA
 biological_processGO:0008360 regulation of cell shape IBA
 biological_processGO:0016055 Wnt signaling pathway IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0030177 positive regulation of Wnt signaling pathway IEA
 biological_processGO:0030178 negative regulation of Wnt signaling pathway IEA
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0032922 circadian regulation of gene expression IEA
 biological_processGO:0034613 cellular protein localization IEA
 biological_processGO:0042752 regulation of circadian rhythm IEA
 biological_processGO:0048511 rhythmic process IEA
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IEA
 biological_processGO:1903827 regulation of cellular protein localization IEA
 biological_processGO:2000052 positive regulation of non-canonical Wnt signaling pathway IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
WNT mediated activation of DVL
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008414 DVL3 / dishevelled segment polarity protein 3 / Q61062* / Q92997* / Segment polarity DVL-3 *  / reaction
 ENSGALG00000001600 DVL1 / dishevelled segment polarity protein 1 / O14640* / P51141* / Segment polarity DVL-1 *  / reaction






 

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