ENSGALG00000008414


Gallus gallus

Features
Gene ID: ENSGALG00000008414
  
Biological name :DVL3
  
Synonyms : dishevelled segment polarity protein 3 / DVL3
  
Possible biological names infered from orthology : Q61062 / Q92997 / Segment polarity DVL-3
  
Species: Gallus gallus
  
Chr. number: 9
Strand: 1
Band:
Gene start: 15837732
Gene end: 15864885
  
Corresponding Affymetrix probe sets: Gga.14806.1.S1_at (Chicken Array)   GgaAffx.5306.1.S1_at (Chicken Array)   GgaAffx.5306.2.S1_at (Chicken Array)   GgaAffx.5306.2.S1_s_at (Chicken Array)   GgaAffx.5306.3.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000045006
Ensembl peptide - ENSGALP00000045254
Ensembl peptide - ENSGALP00000013689
NCBI entrez gene - 424949     See in Manteia.
RefSeq - XM_015291567
RefSeq - XM_015291563
RefSeq - XM_015291565
RefSeq - XM_015291566
RefSeq - XM_004943394
RefSeq - XM_015291562
swissprot - A0A1D5NY00
swissprot - F1P5N3
swissprot - A0A1D5NXB2
Ensembl - ENSGALG00000008414
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DVL3ENSG00000161202Homo sapiens
 Dvl3ENSMUSG00000003233Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DVL1 / dishevelled segment polarity protein 1 / O14640* / P51141* / Segment polarity DVL-1 *ENSGALG0000000160069
DIXDC1 / DIX domain containing 1 / Dixin * / Q155Q3* / Q80Y83*ENSGALG0000000792912


Protein motifs (from Interpro)
Interpro ID Name
 IPR000591  DEP domain
 IPR001158  DIX domain
 IPR001478  PDZ domain
 IPR003351  Dishevelled protein domain
 IPR008339  Dishevelled family
 IPR008342  Dishevelled-3
 IPR011991  ArsR-like helix-turn-helix domain
 IPR015506  Dishevelled-related protein
 IPR024580  Dishevelled C-terminal
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001934 positive regulation of protein phosphorylation IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0035567 non-canonical Wnt signaling pathway IEA
 biological_processGO:0043507 positive regulation of JUN kinase activity IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0050821 protein stabilization IEA
 biological_processGO:0060070 canonical Wnt signaling pathway IEA
 biological_processGO:0060071 Wnt signaling pathway, planar cell polarity pathway IEA
 biological_processGO:0090179 planar cell polarity pathway involved in neural tube closure IBA
 biological_processGO:1903827 regulation of cellular protein localization IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0002020 protease binding IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005109 frizzled binding IEA
 molecular_functionGO:0008013 beta-catenin binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0048365 Rac GTPase binding IEA


Pathways (from Reactome)
Pathway description
WNT mediated activation of DVL
Degradation of DVL
Disassembly of the destruction complex and recruitment of AXIN to the membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000000518 KLHL12 / kelch like family member 12 / Q53G59* / Q8BZM0* / Kelch-like protein 12 *  / complex / reaction
 ENSGALG00000042657 WNT3A / Q2LMP1 / Protein Wnt-3a / P56704* / P27467* / Wnt family member 3A* / wingless-type MMTV integration site family, member 3A*  / complex
 ENSGALG00000029402 AXIN1 / O15169*  / reaction / complex
 ENSGALG00000015107 PIP5K1B / phosphatidylinositol 4-phosphate 5-kinase type-1 beta / O14986* / P70181*  / complex / reaction
 ENSGALG00000031503 LRP6 / LDL receptor related protein 6 / O75581*  / complex
 ENSGALG00000005108 CUL3 / cullin 3 / Q13618* / Q9JLV5*  / complex / reaction
 ENSGALG00000011993 RBX1 / ring-box 1 / P62877* / P62878* / E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase RBX1, N-terminally processed*  / complex / reaction
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / reaction
 ENSGALG00000032257 CSNK1E / Q5ZLL1 / Casein kinase I isoform epsilon / Q9JMK2* / P49674* / Z98749.3* / casein kinase 1 epsilon*  / reaction
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / reaction






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr