ENSDARG00000052765


Danio rerio

Features
Gene ID: ENSDARG00000052765
  
Biological name :gria2b
  
Synonyms : glutamate receptor, ionotropic, AMPA 2b / gria2b
  
Possible biological names infered from orthology : glutamate ionotropic receptor AMPA type subunit 2 / glutamate receptor 2 isoform 3 / GRIA2 / P42262
  
Species: Danio rerio
  
Chr. number: 14
Strand: 1
Band:
Gene start: 35748206
Gene end: 35813662
  
Corresponding Affymetrix probe sets: Dr.12571.1.S1_at (Zebrafish Array)   Dr.25522.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000142212
Ensembl peptide - ENSDARP00000144219
Ensembl peptide - ENSDARP00000142456
Ensembl peptide - ENSDARP00000064616
Ensembl peptide - ENSDARP00000069157
NCBI entrez gene - 170451     See in Manteia.
RefSeq - XM_005157304
RefSeq - XM_005157305
RefSeq - XM_005157306
swissprot - F1QQC1
swissprot - A0A140LGS7
swissprot - A0A140LG34
swissprot - F1QKT1
ZFIN ID - ZDB-GENE-020125-4
Ensembl - ENSDARG00000052765
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GRIA2ENSGALG00000009405Gallus gallus
 GRIA2ENSG00000120251Homo sapiens
 Gria2ENSMUSG00000033981Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gria2a / glutamate receptor, ionotropic, AMPA 2a / GRIA2* / P42262* / glutamate receptor 2 isoform 3 * / glutamate ionotropic receptor AMPA type subunit 2*ENSDARG0000007017388
gria4a / glutamate receptor, ionotropic, AMPA 4aENSDARG0000003749670
gria4b / glutamate receptor, ionotropic, AMPA 4bENSDARG0000005936870
gria1a / glutamate receptor, ionotropic, AMPA 1a / GRIA1* / P23818* / P42261* / Glutamate receptor 1 * / glutamate ionotropic receptor AMPA type subunit 1*ENSDARG0000002135267
gria3b / glutamate receptor, ionotropic, AMPA 3b / GRIA3* / P42263* / Q9Z2W9* / glutamate ionotropic receptor AMPA type subunit 3* / Mus musculus glutamate receptor, ionotropic, AMPA3 (alph...ENSDARG0000003749867
gria3a / glutamate receptor, ionotropic, AMPA 3a / GRIA3* / P42263* / Q9Z2W9* / glutamate ionotropic receptor AMPA type subunit 3* / Mus musculus glutamate receptor, ionotropic, AMPA3 (alph...ENSDARG0000003273766
gria1b / glutamate receptor, ionotropic, AMPA 1b / GRIA1* / P23818* / P42261* / Glutamate receptor 1 * / glutamate ionotropic receptor AMPA type subunit 1*ENSDARG0000003271466
GRIK2 / glutamate ionotropic receptor kainate type subunit 2 / P39087* / Q13002* / Glutamate receptor ionotropic, kainate 2 *ENSDARG0000011377138
grik1b / glutamate receptor, ionotropic, kainate 1b / GRIK1* / P39086* / glutamate ionotropic receptor kainate type subunit 1* / Mus musculus glutamate receptor, ionotropic, kainate 1 (Grik...ENSDARG0000004062737
grik1a / glutamate receptor, ionotropic, kainate 1a / GRIK1* / P39086* / glutamate ionotropic receptor kainate type subunit 1* / Mus musculus glutamate receptor, ionotropic, kainate 1 (Grik...ENSDARG0000006913936
GRIK3 / glutamate ionotropic receptor kainate type subunit 3 / Q13003*ENSDARG0000007771535
grik4 / glutamate receptor, ionotropic, kainate 4 / Q16099* / Q8BMF5* / glutamate ionotropic receptor kainate type subunit 4*ENSDARG0000002675334
grik5 / glutamate receptor, ionotropic, kainate 5 / Q16478* / Q61626* / glutamate ionotropic receptor kainate type subunit 5*ENSDARG0000010144933
grid1b / glutamate receptor, ionotropic, delta 1b / GRID1* / Q61627* / Q9ULK0* / Glutamate receptor ionotropic, delta-1 * / glutamate ionotropic receptor delta type subunit 1*ENSDARG0000004416126
grid1a / glutamate receptor, ionotropic, delta 1a / GRID1* / Q61627* / Q9ULK0* / Glutamate receptor ionotropic, delta-1 * / glutamate ionotropic receptor delta type subunit 1*ENSDARG0000007458326
grid2 / glutamate receptor, ionotropic, delta 2 / O43424* / Q61625* / glutamate ionotropic receptor delta type subunit 2*ENSDARG0000005530223
grin2bb / glutamate receptor, ionotropic, N-methyl D-aspartate 2B, genome duplicate b / GRIN2B* / Q13224* / glutamate receptor, ionotropic, NMDA2B (epsilon 2)* / glutamate ionotropic recept...ENSDARG0000003037621
grin2ca / glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca / Q14957* / GRIN2C* / Q01098* / Glutamate receptor ionotropic, NMDA 2C * / glutamate ionotropic receptor NMDA type subunit 2C*ENSDARG0000007814920
grin1a / glutamate receptor, ionotropic, N-methyl D-aspartate 1a / GRIN1* / P35438* / Q05586* / Glutamate receptor ionotropic, NMDA 1 * / glutamate ionotropic receptor NMDA type subunit 1*ENSDARG0000002782820
grin2aa / glutamate receptor, ionotropic, N-methyl D-aspartate 2A, a / Q12879* / GRIN2A* / P35436* / Glutamate receptor ionotropic, NMDA 2A * / glutamate ionotropic receptor NMDA type subunit 2A*ENSDARG0000003449320


Protein motifs (from Interpro)
Interpro ID Name
 IPR001320  Ionotropic glutamate receptor
 IPR001508  Ionotropic glutamate receptor, metazoa
 IPR001828  Receptor, ligand binding region
 IPR019594  Ionotropic glutamate receptor, L-glutamate and glycine-binding domain
 IPR028082  Periplasmic binding protein-like I


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0035235 ionotropic glutamate receptor signaling pathway IEA
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0032281 AMPA glutamate receptor complex IBA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004970 ionotropic glutamate receptor activity IEA
 molecular_functionGO:0004971 AMPA glutamate receptor activity IBA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005234 extracellularly glutamate-gated ion channel activity IEA


Pathways (from Reactome)
Pathway description
Activation of AMPA receptors
Trafficking of GluR2-containing AMPA receptors
Unblocking of NMDA receptor, glutamate binding and activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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