ENSDARG00000032714


Danio rerio

Features
Gene ID: ENSDARG00000032714
  
Biological name :gria1b
  
Synonyms : glutamate receptor, ionotropic, AMPA 1b / gria1b
  
Possible biological names infered from orthology : glutamate ionotropic receptor AMPA type subunit 1 / Glutamate receptor 1 / GRIA1 / P23818 / P42261
  
Species: Danio rerio
  
Chr. number: 21
Strand: -1
Band:
Gene start: 26152332
Gene end: 26250744
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000044734
Ensembl peptide - ENSDARP00000111368
Ensembl peptide - ENSDARP00000112822
NCBI entrez gene - 403044     See in Manteia.
RefSeq - NM_205730
RefSeq Peptide - NP_991293
swissprot - F1RE87
swissprot - E7F1V8
swissprot - Q71E64
ZFIN ID - ZDB-GENE-020125-2
Ensembl - ENSDARG00000032714
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GRIA1ENSGALG00000004083Gallus gallus
 GRIA1ENSG00000155511Homo sapiens
 Gria1ENSMUSG00000020524Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gria1a / glutamate receptor, ionotropic, AMPA 1a / GRIA1* / P23818* / P42261* / Glutamate receptor 1 * / glutamate ionotropic receptor AMPA type subunit 1*ENSDARG0000002135283
gria2b / glutamate receptor, ionotropic, AMPA 2b / GRIA2* / P42262* / glutamate receptor 2 isoform 3 * / glutamate ionotropic receptor AMPA type subunit 2*ENSDARG0000005276565
gria4b / glutamate receptor, ionotropic, AMPA 4bENSDARG0000005936864
gria2a / glutamate receptor, ionotropic, AMPA 2a / GRIA2* / P42262* / glutamate receptor 2 isoform 3 * / glutamate ionotropic receptor AMPA type subunit 2*ENSDARG0000007017363
gria3a / glutamate receptor, ionotropic, AMPA 3a / GRIA3* / P42263* / Q9Z2W9* / glutamate ionotropic receptor AMPA type subunit 3* / Mus musculus glutamate receptor, ionotropic, AMPA3 (alph...ENSDARG0000003273763
gria4a / glutamate receptor, ionotropic, AMPA 4aENSDARG0000003749663
gria3b / glutamate receptor, ionotropic, AMPA 3b / GRIA3* / P42263* / Q9Z2W9* / glutamate ionotropic receptor AMPA type subunit 3* / Mus musculus glutamate receptor, ionotropic, AMPA3 (alph...ENSDARG0000003749863
GRIK2 / glutamate ionotropic receptor kainate type subunit 2 / P39087* / Q13002* / Glutamate receptor ionotropic, kainate 2 *ENSDARG0000011377138
grik1b / glutamate receptor, ionotropic, kainate 1b / GRIK1* / P39086* / glutamate ionotropic receptor kainate type subunit 1* / Mus musculus glutamate receptor, ionotropic, kainate 1 (Grik...ENSDARG0000004062737
grik1a / glutamate receptor, ionotropic, kainate 1a / GRIK1* / P39086* / glutamate ionotropic receptor kainate type subunit 1* / Mus musculus glutamate receptor, ionotropic, kainate 1 (Grik...ENSDARG0000006913937
GRIK3 / glutamate ionotropic receptor kainate type subunit 3 / Q13003*ENSDARG0000007771536
grik5 / glutamate receptor, ionotropic, kainate 5 / Q16478* / Q61626* / glutamate ionotropic receptor kainate type subunit 5*ENSDARG0000010144934
grik4 / glutamate receptor, ionotropic, kainate 4 / Q16099* / Q8BMF5* / glutamate ionotropic receptor kainate type subunit 4*ENSDARG0000002675334
grid1a / glutamate receptor, ionotropic, delta 1a / GRID1* / Q61627* / Q9ULK0* / Glutamate receptor ionotropic, delta-1 * / glutamate ionotropic receptor delta type subunit 1*ENSDARG0000007458326
grid1b / glutamate receptor, ionotropic, delta 1b / GRID1* / Q61627* / Q9ULK0* / Glutamate receptor ionotropic, delta-1 * / glutamate ionotropic receptor delta type subunit 1*ENSDARG0000004416125
grid2 / glutamate receptor, ionotropic, delta 2 / O43424* / Q61625* / glutamate ionotropic receptor delta type subunit 2*ENSDARG0000005530224
grin2bb / glutamate receptor, ionotropic, N-methyl D-aspartate 2B, genome duplicate b / GRIN2B* / Q13224* / glutamate receptor, ionotropic, NMDA2B (epsilon 2)* / glutamate ionotropic recept...ENSDARG0000003037621
grin1b / glutamate receptor, ionotropic, N-methyl D-aspartate 1b / GRIN1* / P35438* / Q05586* / Glutamate receptor ionotropic, NMDA 1 * / glutamate ionotropic receptor NMDA type subunit 1*ENSDARG0000002572820
grin2ab / glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b / Q12879* / GRIN2A* / P35436* / Glutamate receptor ionotropic, NMDA 2A * / glutamate ionotropic receptor NMDA type subunit 2A*ENSDARG0000007054320
grin1a / glutamate receptor, ionotropic, N-methyl D-aspartate 1a / GRIN1* / P35438* / Q05586* / Glutamate receptor ionotropic, NMDA 1 * / glutamate ionotropic receptor NMDA type subunit 1*ENSDARG0000002782820


Protein motifs (from Interpro)
Interpro ID Name
 IPR001320  Ionotropic glutamate receptor
 IPR001828  Receptor, ligand binding region
 IPR019594  Ionotropic glutamate receptor, L-glutamate and glycine-binding domain
 IPR028082  Periplasmic binding protein-like I


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0035235 ionotropic glutamate receptor signaling pathway IEA
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0032281 AMPA glutamate receptor complex IBA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004970 ionotropic glutamate receptor activity IEA
 molecular_functionGO:0004971 AMPA glutamate receptor activity IBA
 molecular_functionGO:0005234 extracellularly glutamate-gated ion channel activity IEA


Pathways (from Reactome)
Pathway description
COPII-mediated vesicle transport
Activation of AMPA receptors
Trafficking of GluR2-containing AMPA receptors
Unblocking of NMDA receptor, glutamate binding and activation
Cargo concentration in the ER
Synaptic adhesion-like molecules


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000037498 gria3b / glutamate receptor, ionotropic, AMPA 3b / GRIA3* / P42263* / Q9Z2W9* / glutamate ionotropic receptor AMPA type subunit 3* / Mus musculus glutamate receptor, ionotropic, AMPA3 (alph...  / reaction / complex
 ENSDARG00000032737 gria3a / glutamate receptor, ionotropic, AMPA 3a / GRIA3* / P42263* / Q9Z2W9* / glutamate ionotropic receptor AMPA type subunit 3* / Mus musculus glutamate receptor, ionotropic, AMPA3 (alph...  / reaction / complex
 ENSDARG00000043662 cnih2 / Q5BL21 / cornichon family AMPA receptor auxiliary protein 2 / 2 * / O35089* / Q6PI25*  / complex / reaction
 ENSDARG00000015053 grip1 / glutamate receptor interacting protein 1 / Q925T6* / Q9Y3R0*  / reaction
 ENSDARG00000030376 grin2bb / glutamate receptor, ionotropic, N-methyl D-aspartate 2B, genome duplicate b / GRIN2B* / Q13224* / glutamate receptor, ionotropic, NMDA2B (epsilon 2)* / glutamate ionotropic recept...  / reaction
 ENSDARG00000032714 gria1b / glutamate receptor, ionotropic, AMPA 1b / GRIA1* / P23818* / P42261* / Glutamate receptor 1 * / glutamate ionotropic receptor AMPA type subunit 1*  / reaction / complex
 ENSDARG00000077560 grin2cb / glutamate receptor, ionotropic, N-methyl D-aspartate 2Cb / Q14957* / GRIN2C* / Q01098* / Glutamate receptor ionotropic, NMDA 2C * / glutamate ionotropic receptor NMDA type subunit 2C*  / reaction
 ENSDARG00000035152 ap2b1 / adaptor-related protein complex 2, beta 1 subunit / P63010* / Q9DBG3* / AP-2 complex subunit beta *  / reaction
 ENSDARG00000002790 Q6NWK2 / ap2m1a / ap2m1b / adaptor-related protein complex 2, mu 1 subunit, b / AP2M1* / Q96CW1* / P84091* / AP-2 complex subunit mu * / adaptor related protein complex 2 mu 1 subunit*  / reaction
 ENSDARG00000070543 grin2ab / glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b / Q12879* / GRIN2A* / P35436* / Glutamate receptor ionotropic, NMDA 2A * / glutamate ionotropic receptor NMDA type subunit 2A*  / reaction
 ENSDARG00000043010 Q6DEH3 / camk2d1 / calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1 / CAMK2D* / Q13557* / Q6PHZ2* / calcium/calmodulin dependent protein kinase II delta* / Mus musculus c...  / reaction
 ENSDARG00000078149 grin2ca / glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca / Q14957* / GRIN2C* / Q01098* / Glutamate receptor ionotropic, NMDA 2C * / glutamate ionotropic receptor NMDA type subunit 2C*  / reaction
 ENSDARG00000026967 ap2s1 / adaptor-related protein complex 2, sigma 1 subunit / P53680* / P62743* / AP-2 complex subunit sigma *  / reaction
 ENSDARG00000014953 cnih3 / cornichon family AMPA receptor auxiliary protein 3 / 3 * / Q6ZWS4* / Q8TBE1*  / complex / reaction
 ENSDARG00000086207 grin2da / glutamate receptor, ionotropic, N-methyl D-aspartate 2D, a / Q03391* / GRIN2D* / O15399* / Glutamate receptor ionotropic, NMDA 2D * / glutamate ionotropic receptor NMDA type subunit 2D*  / reaction
 ENSDARG00000033899 ap2m1b / adaptor-related protein complex 2, mu 1 subunit, b / AP2M1* / Q96CW1* / P84091* / AP-2 complex subunit mu * / adaptor related protein complex 2 mu 1 subunit*  / reaction






 

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