ENSDARG00000053087


Danio rerio

Features
Gene ID: ENSDARG00000053087
  
Biological name :mthfr
  
Synonyms : methylenetetrahydrofolate reductase (NAD(P)H) / mthfr
  
Possible biological names infered from orthology : methylenetetrahydrofolate reductase / P42898 / Q9WU20
  
Species: Danio rerio
  
Chr. number: 8
Strand: 1
Band:
Gene start: 47219107
Gene end: 47252552
  
Corresponding Affymetrix probe sets: Dr.6873.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000121987
Ensembl peptide - ENSDARP00000069553
NCBI entrez gene - 567547     See in Manteia.
RefSeq - NM_001128255
RefSeq - NM_001281840
RefSeq Peptide - NP_001121727
RefSeq Peptide - NP_001268769
swissprot - B0V153
ZFIN ID - ZDB-GENE-041111-215
Ensembl - ENSDARG00000053087
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MTHFRENSGALG00000004612Gallus gallus
 MTHFRENSG00000177000Homo sapiens
 MthfrENSMUSG00000029009Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003171  Methylenetetrahydrofolate reductase
 IPR004621  Eukaryotic-type methylenetetrahydrofolate reductase
 IPR029041  FAD-linked oxidoreductase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006555 methionine metabolic process IEA
 biological_processGO:0006730 one-carbon metabolic process IBA
 biological_processGO:0035999 tetrahydrofolate interconversion IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity IBA
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
Metabolism of folate and pterines


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000053087 mthfr / methylenetetrahydrofolate reductase (NAD(P)H) / P42898* / Q9WU20* / methylenetetrahydrofolate reductase*  / complex






 

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© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr