ENSGALG00000004612


Gallus gallus

Features
Gene ID: ENSGALG00000004612
  
Biological name :MTHFR
  
Synonyms : Gallus gallus methylenetetrahydrofolate reductase (MTHFR), mRNA. / MTHFR
  
Possible biological names infered from orthology : methylenetetrahydrofolate reductase / P42898 / Q9WU20
  
Species: Gallus gallus
  
Chr. number: 21
Strand: 1
Band:
Gene start: 5605982
Gene end: 5613569
  
Corresponding Affymetrix probe sets: GgaAffx.2862.1.S1_s_at (Chicken Array)   GgaAffx.2862.3.S1_s_at (Chicken Array)   GgaAffx.2862.6.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000007330
NCBI entrez gene - 419489     See in Manteia.
RefSeq - NM_001328491
RefSeq - XM_015297209
RefSeq - XM_417645
RefSeq Peptide - NP_001315420
swissprot - E1BXL1
Ensembl - ENSGALG00000004612
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mthfrENSDARG00000053087Danio rerio
 MTHFRENSG00000177000Homo sapiens
 MthfrENSMUSG00000029009Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003171  Methylenetetrahydrofolate reductase
 IPR004621  Eukaryotic-type methylenetetrahydrofolate reductase
 IPR029041  FAD-linked oxidoreductase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006555 methionine metabolic process IEA
 biological_processGO:0006730 one-carbon metabolic process IBA
 biological_processGO:0031060 regulation of histone methylation IEA
 biological_processGO:0035999 tetrahydrofolate interconversion IEA
 biological_processGO:0050667 homocysteine metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0070829 heterochromatin maintenance IEA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity IBA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0044877 protein-containing complex binding IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IEA
 molecular_functionGO:0072341 modified amino acid binding IEA


Pathways (from Reactome)
Pathway description
Metabolism of folate and pterines


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000004612 MTHFR / Gallus gallus methylenetetrahydrofolate reductase (MTHFR), mRNA. / P42898* / Q9WU20* / methylenetetrahydrofolate reductase*  / complex






 

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