ENSDARG00000053666


Danio rerio

Features
Gene ID: ENSDARG00000053666
  
Biological name :myb
  
Synonyms : myb / v-myb avian myeloblastosis viral oncogene homolog
  
Possible biological names infered from orthology : MYB proto-oncogene, transcription factor / P06876 / P10242 / Transcriptional activator Myb
  
Species: Danio rerio
  
Chr. number: 23
Strand: 1
Band:
Gene start: 31815423
Gene end: 31830043
  
Corresponding Affymetrix probe sets: Dr.8106.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000070211
Ensembl peptide - ENSDARP00000070207
NCBI entrez gene - 30519     See in Manteia.
RefSeq - NM_001309822
RefSeq Peptide - NP_001296751
swissprot - F1QP25
swissprot - F1QP24
ZFIN ID - ZDB-GENE-991110-14
Ensembl - ENSDARG00000053666
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MYBENSGALG00000013956Gallus gallus
 MYBENSG00000118513Homo sapiens
 MybENSMUSG00000019982Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mybl1 / v-myb avian myeloblastosis viral oncogene homolog-like 1 / P10243* / MYB proto-oncogene like 1*ENSDARG0000003099943
mybl2b / v-myb avian myeloblastosis viral oncogene homolog-like 2b / MYBL2* / P10244* / P48972* / Myb-related protein B * / MYB proto-oncogene like 2*ENSDARG0000003226432
mybl2a / v-myb avian myeloblastosis viral oncogene homolog-like 2aENSDARG0000009524122
snapc4 / small nuclear RNA activating complex, polypeptide 4 / Q5SXM2* / Q8BP86* / snRNA-activating protein complex subunit 4 *ENSDARG0000006767316


Protein motifs (from Interpro)
Interpro ID Name
 IPR001005  SANT/Myb domain
 IPR009057  Homeobox-like domain superfamily
 IPR012642  Transcription regulator Wos2-domain
 IPR015395  C-myb, C-terminal
 IPR017930  Myb domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IBA
 biological_processGO:0001654 eye development IMP
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0035701 hematopoietic stem cell migration IGI
 biological_processGO:0043009 chordate embryonic development IMP
 biological_processGO:0045658 regulation of neutrophil differentiation IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IBA
 biological_processGO:0060216 definitive hemopoiesis IMP
 biological_processGO:0060271 cilium assembly IMP
 cellular_componentGO:0000785 chromatin IDA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IGI
 molecular_functionGO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IBA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000094 blood island blood island erythroid lineage cell decreased amount , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000114 heart heart edematous , abnormal
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 ZFA:0000669 head kidney head kidney blood cell decreased amount , abnormal
head kidney lacks parts or has fewer parts of type hematopoietic multipotent progenitor cell , abnormal
head kidney has fewer parts of type hematopoietic multipotent progenitor cell hemoglobin complex, abnormal
Show

 ZFA:0001094 whole organism whole organism decreased size , abnormal
whole organism decreased life span , abnormal
whole organism dead , abnormal
whole organism hemoglobin complex decreased amount , abnormal
Show

 ZFA:0001115 trunk trunk decreased length , abnormal
Show

 ZFA:0005028 ventral wall of dorsal aorta ventral wall of dorsal aorta hematopoietic stem cell increased amount , abnormal
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 ZFA:0005242 multi-ciliated epithelial cell multi-ciliated epithelial cell cilium physical object quality , abnormal
Show

 ZFA:0009014 hematopoietic stem cell hematopoietic stem cell increased accumulation ventral wall of dorsal aorta , abnormal
Show

 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte increased amount , abnormal
nucleate erythrocyte absent , abnormal
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 ZFA:0009323 thrombocyte thrombocyte decreased amount , abnormal
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 ZFA:0009327 neutrophil neutrophil granular vesicle decreased amount , abnormal
neutrophil decreased amount , abnormal
neutrophil absent , abnormal
neutrophil immature , abnormal
Show

 ZFA:0009350 pro-T cell pro-T cell absent , abnormal
Show

 ZFA:0009352 neutrophil progenitor cell neutrophil progenitor cell decreased amount , abnormal
Show

 ZFA:0009355 lymphoid progenitor cell lymphoid progenitor cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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