ENSDARG00000053939


Danio rerio

Features
Gene ID: ENSDARG00000053939
  
Biological name :tgfa
  
Synonyms : tgfa / transforming growth factor, alpha
  
Possible biological names infered from orthology : P01135 / P48030
  
Species: Danio rerio
  
Chr. number: 6
Strand: 1
Band:
Gene start: 40992409
Gene end: 41009381
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000070540
Ensembl peptide - ENSDARP00000125933
NCBI entrez gene - 100034402     See in Manteia.
RefSeq - NM_001144052
RefSeq Peptide - NP_001137524
swissprot - I3ISP4
swissprot - Q7T011
ZFIN ID - ZDB-GENE-040724-208
Ensembl - ENSDARG00000053939
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TGFAENSGALG00000024024Gallus gallus
 TGFAENSG00000163235Homo sapiens
 TgfaENSMUSG00000029999Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
btc / betacellulin, epidermal growth factor family member / P35070* / Q05928* / betacellulin* / Probetacellulin Betacellulin*ENSDARG0000009811215


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR013032  EGF-like, conserved site
 IPR015497  Epidermal growth factor receptor ligand


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity IBA
 biological_processGO:0007173 epidermal growth factor receptor signaling pathway IBA
 biological_processGO:0008284 positive regulation of cell proliferation IBA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005154 epidermal growth factor receptor binding IBA
 molecular_functionGO:0008083 growth factor activity IBA


Pathways (from Reactome)
Pathway description
COPII-mediated vesicle transport
Cargo concentration in the ER


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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