ENSDARG00000054199


Danio rerio

Features
Gene ID: ENSDARG00000054199
  
Biological name :mthfd2l
  
Synonyms : methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like / mthfd2l
  
Possible biological names infered from orthology : D3YZG8 / Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 NAD-dependent methylenetetrahydrofolate dehydrogenase Methenyltetrahydrofolate cyclohydrolase / Q9H903
  
Species: Danio rerio
  
Chr. number: 8
Strand: 1
Band:
Gene start: 32389838
Gene end: 32403826
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000070824
Ensembl peptide - ENSDARP00000123417
NCBI entrez gene - 327496     See in Manteia.
RefSeq - NM_199813
RefSeq Peptide - NP_956107
swissprot - F1QXT9
swissprot - E9QC23
ZFIN ID - ZDB-GENE-030131-5707
Ensembl - ENSDARG00000054199
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MTHFD2LENSGALG00000010855Gallus gallus
 Q9H903ENSG00000163738Homo sapiens
 D3YZG8ENSMUSG00000029376Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mthfd2 / methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase / P13995* / P18155* / Bifunctional methylenetetrahydrofolate dehydrogenase/cycl...ENSDARG0000009864658


Protein motifs (from Interpro)
Interpro ID Name
 IPR000672  Tetrahydrofolate dehydrogenase/cyclohydrolase
 IPR016040  NAD(P)-binding domain
 IPR020630  Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
 IPR020631  Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
 IPR020867  Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006730 one-carbon metabolic process IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IBA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004477 methenyltetrahydrofolate cyclohydrolase activity IBA
 molecular_functionGO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity IBA
 molecular_functionGO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity IEA


Pathways (from Reactome)
Pathway description
Metabolism of folate and pterines


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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