ENSDARG00000054823


Danio rerio

Features
Gene ID: ENSDARG00000054823
  
Biological name :id3
  
Synonyms : id3 / inhibitor of DNA binding 3
  
Possible biological names infered from orthology : DNA-binding protein inhibitor ID-3 / inhibitor of DNA binding 3, HLH protein / P41133 / Q02535
  
Species: Danio rerio
  
Chr. number: 17
Strand: -1
Band:
Gene start: 27271399
Gene end: 27273296
  
Corresponding Affymetrix probe sets: Dr.7103.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000071555
NCBI entrez gene - 246093     See in Manteia.
RefSeq - NM_152967
RefSeq Peptide - NP_694499
swissprot - Q8QFX4
ZFIN ID - ZDB-GENE-020515-1
Ensembl - ENSDARG00000054823
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ID3ENSGALG00000035317Gallus gallus
 ID3ENSG00000117318Homo sapiens
 Id3ENSMUSG00000007872Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
id2a / inhibitor of DNA binding 2a / ID2* / P41136* / Q02363* / inhibitor of DNA binding 2* / DNA-binding protein inhibitor ID-2 *ENSDARG0000005528352
id2b / inhibitor of DNA binding 2b / ID2* / P41136* / Q02363* / inhibitor of DNA binding 2* / DNA-binding protein inhibitor ID-2 *ENSDARG0000002954449
id1 / inhibitor of DNA binding 1 / P20067* / P41134* / inhibitor of DNA binding 1, HLH protein*ENSDARG0000004076447
id4 / inhibitor of DNA binding 4 / P41139* / P47928* / DNA-binding protein inhibitor ID-4 * / inhibitor of DNA binding 4, HLH protein*ENSDARG0000004513141


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR026052  DNA-binding protein inhibitor


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0071542 dopaminergic neuron differentiation IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain morphology , abnormal
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 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary malformed , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000110 fourth ventricle fourth ventricle increased size , abnormal
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 ZFA:0000445 optic tectum optic tectum decreased size , abnormal
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 ZFA:0000633 caudal tuberculum caudal tuberculum has fewer parts of type dopaminergic neuron , abnormal
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 ZFA:0001114 head head decreased size , abnormal
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 ZFA:0001115 trunk trunk decreased size , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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