ENSDARG00000055283


Danio rerio

Features
Gene ID: ENSDARG00000055283
  
Biological name :id2a
  
Synonyms : id2a / inhibitor of DNA binding 2a
  
Possible biological names infered from orthology : DNA-binding protein inhibitor ID-2 / ID2 / inhibitor of DNA binding 2 / P41136 / Q02363
  
Species: Danio rerio
  
Chr. number: 17
Strand: 1
Band:
Gene start: 34805897
Gene end: 34808165
  
Corresponding Affymetrix probe sets: Dr.5428.1.S1_at (Zebrafish Array)   NM_201291_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000072092
Ensembl peptide - ENSDARP00000122878
NCBI entrez gene - 266599     See in Manteia.
RefSeq - NM_201291
RefSeq Peptide - NP_958448
swissprot - Q7SZQ2
ZFIN ID - ZDB-GENE-020910-1
Ensembl - ENSDARG00000055283
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ID2ENSGALG00000035016Gallus gallus
 ID2ENSG00000115738Homo sapiens
 Id2ENSMUSG00000020644Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
id2b / inhibitor of DNA binding 2b / ID2* / P41136* / Q02363* / inhibitor of DNA binding 2* / DNA-binding protein inhibitor ID-2 *ENSDARG0000002954452
id3 / inhibitor of DNA binding 3 / P41133* / Q02535* / DNA-binding protein inhibitor ID-3 * / inhibitor of DNA binding 3, HLH protein*ENSDARG0000005482344
id1 / inhibitor of DNA binding 1 / P20067* / P41134* / inhibitor of DNA binding 1, HLH protein*ENSDARG0000004076441
id4 / inhibitor of DNA binding 4 / P41139* / P47928* / DNA-binding protein inhibitor ID-4 * / inhibitor of DNA binding 4, HLH protein*ENSDARG0000004513140


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR026052  DNA-binding protein inhibitor


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001889 liver development IMP
 biological_processGO:0008593 regulation of Notch signaling pathway IMP
 biological_processGO:0031573 intra-S DNA damage checkpoint IMP
 biological_processGO:0045664 regulation of neuron differentiation IMP
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0046532 regulation of photoreceptor cell differentiation IMP
 biological_processGO:1902866 regulation of retina development in camera-type eye IMP
 biological_processGO:2000495 regulation of cell proliferation involved in compound eye morphogenesis IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain decreased size , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
eye cell decreased amount , abnormal
Show

 ZFA:0000119 retinal inner nuclear layer retinal inner nuclear layer unstructured , abnormal
retinal inner nuclear layer cell undifferentiated , abnormal
Show

 ZFA:0000123 liver liver decreased amount , abnormal
Show

 ZFA:0000152 retina retina increased amount , abnormal
retina increased distribution , abnormal
retina cell amount , ameliorated
retina cell decreased amount , abnormal
retina cell proliferation process quality , abnormal
retina cell proliferation process quality , ameliorated
Show

 ZFA:0001464 retinal outer nuclear layer retinal outer nuclear layer unstructured , abnormal
retinal outer nuclear layer cell undifferentiated , abnormal
Show

 ZFA:0009255 amacrine cell amacrine cell absent , abnormal
amacrine cell amount , ameliorated
Show

 ZFA:0009262 retinal cone cell retinal cone cell absent , abnormal
retinal cone cell amount , ameliorated
Show

 ZFA:0009275 retinal rod cell retinal rod cell decreased amount , abnormal
Show

 ZFA:0009280 Muller cell Muller cell decreased amount , abnormal
Show

 ZFA:0009318 retinal bipolar neuron retinal bipolar neuron absent , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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