ENSG00000117318


Homo sapiens

Features
Gene ID: ENSG00000117318
  
Biological name :ID3
  
Synonyms : ID3 / inhibitor of DNA binding 3, HLH protein / Q02535
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p36.12
Gene start: 23557918
Gene end: 23559794
  
Corresponding Affymetrix probe sets: 207826_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000363689
NCBI entrez gene - 3399     See in Manteia.
OMIM - 600277
RefSeq - NM_002167
RefSeq Peptide - NP_002158
swissprot - Q02535
Ensembl - ENSG00000117318
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 id3ENSDARG00000054823Danio rerio
 ID3ENSGALG00000035317Gallus gallus
 Id3ENSMUSG00000007872Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ID4 / P47928 / inhibitor of DNA binding 4, HLH proteinENSG0000017220146
ID1 / P41134 / inhibitor of DNA binding 1, HLH proteinENSG0000012596843
ID2 / Q02363 / inhibitor of DNA binding 2ENSG0000011573843


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR026052  DNA-binding protein inhibitor
 IPR036638  Helix-loop-helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001656 metanephros development IEA
 biological_processGO:0006275 regulation of DNA replication IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development TAS
 biological_processGO:0007417 central nervous system development IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0007517 muscle organ development IEA
 biological_processGO:0007623 circadian rhythm IEA
 biological_processGO:0009611 response to wounding IEA
 biological_processGO:0010629 negative regulation of gene expression IEA
 biological_processGO:0030182 neuron differentiation IEA
 biological_processGO:0030855 epithelial cell differentiation IEA
 biological_processGO:0030903 notochord development IEA
 biological_processGO:0042476 odontogenesis IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity IDA
 biological_processGO:0045662 negative regulation of myoblast differentiation IEA
 biological_processGO:0045668 negative regulation of osteoblast differentiation IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0048511 rhythmic process IEA
 biological_processGO:0051726 regulation of cell cycle IEA
 biological_processGO:0072750 cellular response to leptomycin B IEA
 cellular_componentGO:0005634 nucleus IC
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003714 transcription corepressor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0046983 protein dimerization activity IEA
 molecular_functionGO:1901707 leptomycin B binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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