ENSG00000172201


Homo sapiens

Features
Gene ID: ENSG00000172201
  
Biological name :ID4
  
Synonyms : ID4 / inhibitor of DNA binding 4, HLH protein / P47928
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: p22.3
Gene start: 19837386
Gene end: 19840684
  
Corresponding Affymetrix probe sets: 209291_at (Human Genome U133 Plus 2.0 Array)   209292_at (Human Genome U133 Plus 2.0 Array)   209293_x_at (Human Genome U133 Plus 2.0 Array)   226933_s_at (Human Genome U133 Plus 2.0 Array)   229386_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000367972
NCBI entrez gene - 3400     See in Manteia.
OMIM - 600581
RefSeq - NM_001546
RefSeq Peptide - NP_001537
swissprot - P47928
Ensembl - ENSG00000172201
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 id4ENSDARG00000045131Danio rerio
 ID4ENSGALG00000039474Gallus gallus
 Id4ENSMUSG00000021379Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ID2 / Q02363 / inhibitor of DNA binding 2ENSG0000011573837
ID3 / Q02535 / inhibitor of DNA binding 3, HLH proteinENSG0000011731834
ID1 / P41134 / inhibitor of DNA binding 1, HLH proteinENSG0000012596832


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR026052  DNA-binding protein inhibitor
 IPR036638  Helix-loop-helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000082 G1/S transition of mitotic cell cycle IEA
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II TAS
 biological_processGO:0007405 neuroblast proliferation IEA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0007623 circadian rhythm IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0021766 hippocampus development IEA
 biological_processGO:0021895 cerebral cortex neuron differentiation IEA
 biological_processGO:0022010 central nervous system myelination IEA
 biological_processGO:0034613 cellular protein localization IEA
 biological_processGO:0045444 fat cell differentiation IEA
 biological_processGO:0045599 negative regulation of fat cell differentiation IEA
 biological_processGO:0045665 negative regulation of neuron differentiation IEA
 biological_processGO:0045669 positive regulation of osteoblast differentiation IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048712 negative regulation of astrocyte differentiation IEA
 biological_processGO:0048715 negative regulation of oligodendrocyte differentiation IEA
 biological_processGO:0060512 prostate gland morphogenesis IEA
 biological_processGO:0060740 prostate gland epithelium morphogenesis IEA
 biological_processGO:0060741 prostate gland stromal morphogenesis IEA
 biological_processGO:0061682 seminal vesicle morphogenesis IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0001085 RNA polymerase II transcription factor binding IEA
 molecular_functionGO:0003714 transcription corepressor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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