ENSDARG00000056228


Danio rerio

Features
Gene ID: ENSDARG00000056228
  
Biological name :pld1a
  
Synonyms : phospholipase D1a / pld1a
  
Possible biological names infered from orthology : phospholipase D1 / PLD1 / Q13393
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 25560556
Gene end: 25632090
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000120802
NCBI entrez gene - 556641     See in Manteia.
RefSeq - NM_001160095
RefSeq Peptide - NP_001153567
swissprot - B0V1J1
ZFIN ID - ZDB-GENE-031002-2
Ensembl - ENSDARG00000056228
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000009252Gallus gallus
 PLD1ENSG00000075651Homo sapiens
 Pld1ENSMUSG00000027695Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pld1b / phospholipase D1b / PLD1* / Q13393* / phospholipase D1*ENSDARG0000005712575
pld2 / phospholipase D2 / O14939* / P97813*ENSDARG0000003426250
si:ch211-168k14.2ENSDARG0000005619125


Protein motifs (from Interpro)
Interpro ID Name
 IPR001683  Phox homologous domain
 IPR001736  Phospholipase D/Transphosphatidylase
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR015679  Phospholipase D family
 IPR025202  Phospholipase D-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IMP
 biological_processGO:0006654 phosphatidic acid biosynthetic process IEA
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0048017 inositol lipid-mediated signaling IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004630 phospholipase D activity IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0035091 phosphatidylinositol binding IEA
 molecular_functionGO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PA
Role of phospholipids in phagocytosis
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001285 intersegmental vessel intersegmental vessel morphology , abnormal
intersegmental vessel decreased length , abnormal
intersegmental vessel irregular spatial pattern , abnormal
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 ZFA:0005021 cerebellar central artery cerebellar central artery disorganized , abnormal
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 ZFA:0005054 inner optic circle inner optic circle decreased amount , abnormal
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 ZFA:0009244 primary motor neuron primary motor neuron branched , abnormal
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 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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