ENSDARG00000056832


Danio rerio

Features
Gene ID: ENSDARG00000056832
  
Biological name :exo1
  
Synonyms : exo1 / exonuclease 1
  
Possible biological names infered from orthology : Q9QZ11 / Q9UQ84
  
Species: Danio rerio
  
Chr. number: 17
Strand: -1
Band:
Gene start: 22563836
Gene end: 22573402
  
Corresponding Affymetrix probe sets: Dr.17858.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000117280
Ensembl peptide - ENSDARP00000147578
Ensembl peptide - ENSDARP00000120931
Ensembl peptide - ENSDARP00000073846
NCBI entrez gene - 406778     See in Manteia.
RefSeq - NM_213469
RefSeq Peptide - NP_998634
swissprot - E9QIA0
swissprot - E9QCH1
swissprot - F1QQM4
ZFIN ID - ZDB-GENE-040426-2828
Ensembl - ENSDARG00000056832
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EXO1ENSGALG00000010748Gallus gallus
 EXO1ENSG00000174371Homo sapiens
 Exo1ENSMUSG00000039748Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006084  XPG/Rad2 endonuclease
 IPR006085  XPG N-terminal
 IPR006086  XPG-I domain
 IPR008918  Helix-hairpin-helix motif, class 2
 IPR019734  Tetratricopeptide repeat
 IPR019974  XPG conserved site
 IPR020045  DNA polymerase I-like, H3TH domain
 IPR029060  PIN-like domain superfamily
 IPR032641  Exonuclease 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0016788 hydrolase activity, acting on ester bonds IEA
 molecular_functionGO:0035312 5"-3" exodeoxyribonuclease activity IEA


Pathways (from Reactome)
Pathway description
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
HDR through Single Strand Annealing (SSA)
HDR through Homologous Recombination (HRR)
Resolution of D-loop Structures through Holliday Junction Intermediates
Homologous DNA Pairing and Strand Exchange
Processing of DNA double-strand break ends
Presynaptic phase of homologous DNA pairing and strand exchange
Regulation of TP53 Activity through Phosphorylation
G2/M DNA damage checkpoint


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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