ENSDARG00000057128


Danio rerio

Features
Gene ID: ENSDARG00000057128
  
Biological name :hadhaa
  
Synonyms : hadhaa / hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha a
  
Possible biological names infered from orthology : HADHA / hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha / hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit / P40939 / Q8BMS1
  
Species: Danio rerio
  
Chr. number: 20
Strand: 1
Band:
Gene start: 47953047
Gene end: 47984895
  
Corresponding Affymetrix probe sets: Dr.765.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000074186
NCBI entrez gene - 553401     See in Manteia.
RefSeq - NM_001105276
RefSeq Peptide - NP_001098746
swissprot - A7YT47
ZFIN ID - ZDB-GENE-031222-5
Ensembl - ENSDARG00000057128
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HADHAENSGALG00000016536Gallus gallus
 HADHAENSG00000084754Homo sapiens
 HadhaENSMUSG00000025745Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
hadhab / hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b / HADHA* / P40939* / Q8BMS1* / hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subun...ENSDARG0000006059480
Q6NYL3 / ehhadh / enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase / Q9DBM2* / Q08426* / enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase* / Peroxisomal bifunctional enzyme Enoyl...ENSDARG0000007002927
hadh / hydroxyacyl-CoA dehydrogenase / Q16836* / Q61425* / Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial *ENSDARG0000003076512


Protein motifs (from Interpro)
Interpro ID Name
 IPR001753  Enoyl-CoA hydratase/isomerase
 IPR006108  3-hydroxyacyl-CoA dehydrogenase, C-terminal
 IPR006176  3-hydroxyacyl-CoA dehydrogenase, NAD binding
 IPR006180  3-hydroxyacyl-CoA dehydrogenase, conserved site
 IPR008927  6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
 IPR012803  Fatty acid oxidation complex, alpha subunit, mitochondrial
 IPR013328  6-phosphogluconate dehydrogenase, domain 2
 IPR016040  NAD(P)-binding domain
 IPR018376  Enoyl-CoA hydratase/isomerase, conserved site
 IPR029045  ClpP/crotonase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006635 fatty acid beta-oxidation IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009617 response to bacterium IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0016507 mitochondrial fatty acid beta-oxidation multienzyme complex IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003857 3-hydroxyacyl-CoA dehydrogenase activity IEA
 molecular_functionGO:0004300 enoyl-CoA hydratase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
Acyl chain remodeling of CL
Beta oxidation of myristoyl-CoA to lauroyl-CoA
Beta oxidation of palmitoyl-CoA to myristoyl-CoA
Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA
Beta oxidation of octanoyl-CoA to hexanoyl-CoA
Beta oxidation of hexanoyl-CoA to butanoyl-CoA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000057128 hadhaa / hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha a / HADHA* / P40939* / hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha*  / complex






 

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