ENSDARG00000057987


Danio rerio

Features
Gene ID: ENSDARG00000057987
  
Biological name :uba3
  
Synonyms : Q7ZVX6 / uba3 / ubiquitin-like modifier activating enzyme 3
  
Possible biological names infered from orthology : Q8C878 / Q8TBC4
  
Species: Danio rerio
  
Chr. number: 11
Strand: -1
Band:
Gene start: 17785182
Gene end: 17803137
  
Corresponding Affymetrix probe sets: Dr.4224.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000127871
Ensembl peptide - ENSDARP00000075198
NCBI entrez gene - 406776     See in Manteia.
RefSeq - NM_213467
RefSeq Peptide - NP_998632
swissprot - B2GSP4
swissprot - Q7ZVX6
swissprot - X1WCC8
ZFIN ID - ZDB-GENE-040426-2825
Ensembl - ENSDARG00000057987
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 UBA3ENSGALG00000013410Gallus gallus
 UBA3ENSG00000144744Homo sapiens
 Uba3ENSMUSG00000030061Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000594  THIF-type NAD/FAD binding fold
 IPR014929  E2 binding
 IPR030468  NEDD8-activating enzyme E1 catalytic subunit
 IPR033127  Ubiquitin-activating enzyme E1, Cys active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0045116 protein neddylation IEA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008641 ubiquitin-like modifier activating enzyme activity IEA
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0016881 acid-amino acid ligase activity IEA
 molecular_functionGO:0019781 NEDD8 activating enzyme activity IEA


Pathways (from Reactome)
Pathway description
Dectin-1 mediated noncanonical NF-kB signaling
NIK-->noncanonical NF-kB signaling
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000007989 nedd8 / neural precursor cell expressed, developmentally down-regulated 8 / P29595* / Q15843*  / complex / reaction
 ENSDARG00000025754 ube2f / Q6NY82 / ubiquitin-conjugating enzyme E2F (putative) / Q969M7* / Q9CY34* / UBE2F-SCLY* / UBE2F-SCLY readthrough (NMD candidate)*  / reaction / complex






 

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