ENSDARG00000058053


Danio rerio

Features
Gene ID: ENSDARG00000058053
  
Biological name :serping1
  
Synonyms : serping1 / serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
  
Possible biological names infered from orthology : P05155 / P97290 / serine (or cysteine) peptidase inhibitor, clade G, member 1 / serpin family G member 1
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 13960655
Gene end: 13972626
  
Corresponding Affymetrix probe sets: Dr.5467.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000119903
NCBI entrez gene - 567801     See in Manteia.
RefSeq - NM_001123285
RefSeq - XM_005166883
RefSeq Peptide - NP_001116757
swissprot - B0V2R7
ZFIN ID - ZDB-GENE-030131-1262
Ensembl - ENSDARG00000058053
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SERPING1ENSGALG00000007381Gallus gallus
 P05155ENSG00000149131Homo sapiens
 P97290ENSMUSG00000023224Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
serpinf2a / serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2a / Q61247* / P08697* / SERPINF2* / serpin family F member 2* / serine (or ...ENSDARG0000007644819
serpinf2b / serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2b / Q61247* / P08697* / SERPINF2* / serpin family F member 2* / serine (or ...ENSDARG0000006138318
serpinf1 / serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 / P36955* / P97298* / serpin family F member 1* / Pigment epithelium-derived factor *ENSDARG0000006904816


Protein motifs (from Interpro)
Interpro ID Name
 IPR000215  Serpin family
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR023796  Serpin domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0030193 regulation of blood coagulation IEA
 biological_processGO:0045916 negative regulation of complement activation IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation
Regulation of Complement cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000044613 c1qa / complement component 1, q subcomponent, A chain / P02745* / P98086* / complement C1q A chain* / Complement C1q subcomponent subunit A *  / complex / reaction
 ENSDARG00000058053 serping1 / serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 / P05155* / P97290* / serpin family G member 1* / serine (or cysteine) peptidase inhibitor, clade G, member 1*  / reaction / complex
 ENSDARG00000100248 c1r / complement component 1, r subcomponent / C1S* / P09871* / complement C1s*  / reaction / complex






 

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