Manteia

ENSDARG00000060002

Danio rerio

Features

Gene ID:	ENSDARG00000060002

Biological name :	ogg1

Synonyms :	8-oxoguanine DNA glycosylase / ogg1

Possible biological names infered from orthology :	8-oxoguanine DNA-glycosylase 1 / O08760 / O15527

Species:	Danio rerio

Chr. number:	8
Strand:	1
Band:
Gene start:	46386601
Gene end:	46406382

Corresponding Affymetrix probe sets:

Cross references:	Ensembl peptide - ENSDARP00000078516 Ensembl peptide - ENSDARP00000112068 NCBI entrez gene - 791194 See in Manteia. swissprot - B0R135 swissprot - B0UYD9 ZFIN ID - ZDB-GENE-070112-932 Ensembl - ENSDARG00000060002

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name

Similarity(%)

No match

Protein motifs (from Interpro)

Interpro ID	Name
IPR003265	HhH-GPD domain
IPR011257	DNA glycosylase
IPR012904	8-oxoguanine DNA glycosylase, N-terminal
IPR023170	Helix-turn-helix, base-excision DNA repair, C-terminal

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0003313	heart rudiment development	IMP
biological_process	GO:0006281	DNA repair	IEA
biological_process	GO:0006284	base-excision repair	IEA
biological_process	GO:0006289	nucleotide-excision repair	IEA
biological_process	GO:0007420	brain development	IMP
biological_process	GO:0010975	regulation of neuron projection development	IMP
biological_process	GO:0043524	negative regulation of neuron apoptotic process	IMP
biological_process	GO:0055013	cardiac muscle cell development	IMP
molecular_function	GO:0003684	damaged DNA binding	IEA
molecular_function	GO:0003824	catalytic activity	IEA
molecular_function	GO:0008534	oxidized purine nucleobase lesion DNA N-glycosylase activity	IEA
molecular_function	GO:0019104	DNA N-glycosylase activity	IBA

Pathways (from Reactome)

Pathway description

Cleavage of the damaged pyrimidine

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
ZFA:0000008	brain	brain apoptotic , abnormal brain atrophied , abnormal brain cell proliferation decreased occurrence , abnormal brain axon extension disrupted , abnormal brain innervation disrupted , abnormal brain ventricular system decreased volume , abnormal brain neuron mislocalised , abnormal	Show
ZFA:0000009	cardiac ventricle	cardiac ventricle shortened , abnormal cardiac ventricle decreased size , abnormal cardiac ventricle decreased thickness , abnormal	Show
ZFA:0000028	heart primordium	heart primordium cell proliferation decreased occurrence , abnormal	Show
ZFA:0000042	midbrain hindbrain boundary	midbrain hindbrain boundary malformed , abnormal	Show
ZFA:0000107	eye	eye apoptotic , abnormal	Show
ZFA:0000128	midbrain	midbrain apoptotic , abnormal midbrain cell proliferation decreased occurrence , abnormal	Show
ZFA:0000159	tectal ventricle	tectal ventricle decreased width , abnormal	Show
ZFA:0000360	heart tube	heart tube decreased length , abnormal heart tube condensed , abnormal	Show
ZFA:0000471	atrium	atrium shortened , abnormal atrium decreased size , abnormal	Show
ZFA:0009019	neuronal stem cell	neuronal stem cell decreased amount , abnormal	Show
ZFA:0009248	neuron	neuron plasma membrane structure , abnormal	Show
ZFA:0009316	cardiac muscle cell	cardiac muscle cell decreased amount , abnormal	Show

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSDARG00000018061	neil1 / nei-like DNA glycosylase 1 / Q8K4Q6* / Q96FI4* / Endonuclease 8-like 1 *	/ reaction

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr