ENSDARG00000018061


Danio rerio

Features
Gene ID: ENSDARG00000018061
  
Biological name :neil1
  
Synonyms : neil1 / nei-like DNA glycosylase 1
  
Possible biological names infered from orthology : Endonuclease 8-like 1 / Q8K4Q6 / Q96FI4
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 26827140
Gene end: 26833100
  
Corresponding Affymetrix probe sets: Dr.20071.1.S1_at (Zebrafish Array)   NM_200283_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000017787
NCBI entrez gene - 393253     See in Manteia.
RefSeq - NM_200283
RefSeq Peptide - NP_956577
swissprot - Q6TGW9
ZFIN ID - ZDB-GENE-040426-994
Ensembl - ENSDARG00000018061
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NEIL1ENSGALG00000001586Gallus gallus
 NEIL1ENSG00000140398Homo sapiens
 Neil1ENSMUSG00000032298Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR010979  Ribosomal protein S13-like, H2TH
 IPR012319  Formamidopyrimidine-DNA glycosylase, catalytic domain
 IPR015371  Endonuclease VIII-like 1, DNA binding
 IPR015886  DNA glycosylase/AP lyase, H2TH DNA-binding


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006284 base-excision repair IEA
 biological_processGO:0006289 nucleotide-excision repair IEA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003684 damaged DNA binding IEA
 molecular_functionGO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity IEA
 molecular_functionGO:0004519 endonuclease activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds IEA


Pathways (from Reactome)
Pathway description
Cleavage of the damaged pyrimidine
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000003749 polb / polymerase (DNA directed), beta / P06746* / Q8K409* / DNA polymerase beta*  / complex / reaction
 ENSDARG00000052553 lig3 / ligase III, DNA, ATP-dependent / P49916* / DNA ligase 3*  / complex / reaction
 ENSDARG00000009494 xrcc1 / X-ray repair complementing defective repair in Chinese hamster cells 1 / P18887* / Q60596* / X-ray repair cross complementing 1*  / reaction / complex
 ENSDARG00000060002 ogg1 / 8-oxoguanine DNA glycosylase / O08760* / O15527* / 8-oxoguanine DNA-glycosylase 1*  / reaction
 ENSDARG00000100455 pnkp / polynucleotide kinase 3-phosphatase / Q96T60*  / complex / reaction






 

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