ENSGALG00000001586


Gallus gallus

Features
Gene ID: ENSGALG00000001586
  
Biological name :NEIL1
  
Synonyms : endonuclease 8-like 1 / NEIL1
  
Possible biological names infered from orthology : nei like DNA glycosylase 1 / Q8K4Q6 / Q96FI4
  
Species: Gallus gallus
  
Chr. number: 10
Strand: 1
Band:
Gene start: 2570401
Gene end: 2574557
  
Corresponding Affymetrix probe sets: GgaAffx.12144.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000043877
Ensembl peptide - ENSGALP00000002406
NCBI entrez gene - 770068     See in Manteia.
RefSeq - XM_015278898
RefSeq - NM_001080876
RefSeq Peptide - NP_001074345
swissprot - A0A1D5NU68
swissprot - F1NLM0
Ensembl - ENSGALG00000001586
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 neil1ENSDARG00000018061Danio rerio
 NEIL1ENSG00000140398Homo sapiens
 Neil1ENSMUSG00000032298Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR010979  Ribosomal protein S13-like, H2TH
 IPR012319  Formamidopyrimidine-DNA glycosylase, catalytic domain
 IPR015371  Endonuclease VIII-like 1, DNA binding
 IPR015886  DNA glycosylase/AP lyase, H2TH DNA-binding


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006284 base-excision repair IEA
 biological_processGO:0006289 nucleotide-excision repair IEA
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0032074 negative regulation of nuclease activity IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003684 damaged DNA binding IEA
 molecular_functionGO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA
 molecular_functionGO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0019104 DNA N-glycosylase activity IEA


Pathways (from Reactome)
Pathway description
Cleavage of the damaged pyrimidine
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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