ENSDARG00000009494


Danio rerio

Features
Gene ID: ENSDARG00000009494
  
Biological name :xrcc1
  
Synonyms : X-ray repair complementing defective repair in Chinese hamster cells 1 / xrcc1
  
Possible biological names infered from orthology : P18887 / Q60596 / X-ray repair cross complementing 1
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 54209504
Gene end: 54248267
  
Corresponding Affymetrix probe sets: Dr.26014.1.A1_at (Zebrafish Array)   NM_001003988_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000023168
Ensembl peptide - ENSDARP00000131012
NCBI entrez gene - 445480     See in Manteia.
RefSeq - NM_001003988
RefSeq Peptide - NP_001003988
swissprot - F1QXI2
swissprot - A0A0R4IBN8
ZFIN ID - ZDB-GENE-040822-30
Ensembl - ENSDARG00000009494
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 XRCC1ENSG00000073050Homo sapiens
 Xrcc1ENSMUSG00000051768Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
zgc:110224 / Xndc1* / Q6ZNB5* / AP002495.1* / Xrcc1 N-terminal domain containing 1* / Putative short transient receptor potential channel 2-like protein *ENSDARG0000003226313


Protein motifs (from Interpro)
Interpro ID Name
 IPR001357  BRCT domain
 IPR002706  DNA-repair protein Xrcc1, N-terminal
 IPR008979  Galactose-binding-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000012 single strand break repair IEA
 biological_processGO:0006284 base-excision repair IBA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003684 damaged DNA binding IEA


Pathways (from Reactome)
Pathway description
Resolution of AP sites via the single-nucleotide replacement pathway
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway
HDR through MMEJ (alt-NHEJ)
Gap-filling DNA repair synthesis and ligation in TC-NER


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000003749 polb / polymerase (DNA directed), beta / P06746* / Q8K409* / DNA polymerase beta*  / reaction / complex
 ENSDARG00000018061 neil1 / nei-like DNA glycosylase 1 / Q8K4Q6* / Q96FI4* / Endonuclease 8-like 1 *  / complex / reaction
 ENSDARG00000043480 rbbp8 / F1R983 / retinoblastoma binding protein 8 / Q80YR6* / Q99708* / RB binding protein 8, endonuclease* / retinoblastoma binding protein 8, endonuclease*  / reaction / complex
 ENSDARG00000040303 nbn / nibrin / Q5I2W8 / O60934* / Q9R207*  / complex / reaction
 ENSDARG00000038917 rad50 / RAD50 homolog, double strand break repair protein / Q92878* / AC116366.3* / RAD50 double strand break repair protein*  / reaction / complex
 ENSDARG00000052553 lig3 / ligase III, DNA, ATP-dependent / P49916* / DNA ligase 3*  / complex
 ENSDARG00000105014 mre11a / MRE11 homolog A, double strand break repair nuclease / MRE11* / P49959* / MRE11 homolog, double strand break repair nuclease*  / reaction / complex
 ENSDARG00000100455 pnkp / polynucleotide kinase 3-phosphatase / Q96T60*  / reaction / complex






 

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