ENSDARG00000061338


Danio rerio

Features
Gene ID: ENSDARG00000061338
  
Biological name :ddx6
  
Synonyms : ddx6 / DEAD (Asp-Glu-Ala-Asp) box helicase 6
  
Possible biological names infered from orthology : DEAD-box helicase 6 / Mus musculus DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 (Ddx6), transcript variant 4, mRNA. / P26196 / P54823
  
Species: Danio rerio
  
Chr. number: 18
Strand: -1
Band:
Gene start: 43865901
Gene end: 43884044
  
Corresponding Affymetrix probe sets: Dr.24222.1.A1_at (Zebrafish Array)   Dr.3865.1.A1_at (Zebrafish Array)   XM_679831_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000081816
Ensembl peptide - ENSDARP00000149027
NCBI entrez gene - 564633     See in Manteia.
RefSeq - XM_679831
swissprot - E7FD91
ZFIN ID - ZDB-GENE-070912-83
Ensembl - ENSDARG00000061338
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DDX6ENSGALG00000033064Gallus gallus
 DDX6ENSG00000110367Homo sapiens
 Ddx6ENSMUSG00000032097Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ddx61 / DEAD (Asp-Glu-Ala-Asp) box helicase 61ENSDARG0000001842578


Protein motifs (from Interpro)
Interpro ID Name
 IPR000629  ATP-dependent RNA helicase DEAD-box, conserved site
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014014  RNA helicase, DEAD-box type, Q motif
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006417 regulation of translation IBA
 biological_processGO:0009408 response to heat IGI
 biological_processGO:0010501 RNA secondary structure unwinding IBA
 biological_processGO:0033962 cytoplasmic mRNA processing body assembly IBA
 biological_processGO:0034063 stress granule assembly IMP
 cellular_componentGO:0000932 P-body IBA
 cellular_componentGO:0005730 nucleolus IBA
 cellular_componentGO:0010494 cytoplasmic stress granule IBA
 cellular_componentGO:0036464 cytoplasmic ribonucleoprotein granule IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IBA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
mRNA decay by 5 to 3 exoribonuclease


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000135 notochord notochord morphology , abnormal
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 ZFA:0000155 somite somite morphology , abnormal
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 ZFA:0001094 whole organism whole organism decreased life span , abnormal
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 ZFA:0001115 trunk trunk cytoplasmic stress granule absent , abnormal
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 ZFA:0001117 post-vent region post-vent region curved , abnormal
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 ZFA:0005024 trunk vasculature trunk vasculature morphology , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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