ENSG00000110367


Homo sapiens

Features
Gene ID: ENSG00000110367
  
Biological name :DDX6
  
Synonyms : DDX6 / DEAD-box helicase 6 / P26196
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q23.3
Gene start: 118747766
Gene end: 118791149
  
Corresponding Affymetrix probe sets: 1562836_at (Human Genome U133 Plus 2.0 Array)   204909_at (Human Genome U133 Plus 2.0 Array)   225549_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000433704
Ensembl peptide - ENSP00000442266
Ensembl peptide - ENSP00000478754
Ensembl peptide - ENSP00000483902
NCBI entrez gene - 1656     See in Manteia.
OMIM - 600326
RefSeq - XM_017017251
RefSeq - NM_001257191
RefSeq - NM_004397
RefSeq - XM_005271417
RefSeq - XM_011542644
RefSeq - XM_011542645
RefSeq Peptide - NP_001244120
RefSeq Peptide - NP_004388
swissprot - P26196
swissprot - Q8IV96
Ensembl - ENSG00000110367
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ddx6ENSDARG00000061338Danio rerio
 DDX6ENSGALG00000033064Gallus gallus
 Ddx6ENSMUSG00000032097Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000629  ATP-dependent RNA helicase DEAD-box, conserved site
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014014  RNA helicase, DEAD-box type, Q motif
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006417 regulation of translation IBA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0010501 RNA secondary structure unwinding IBA
 biological_processGO:0019074 viral RNA genome packaging IMP
 biological_processGO:0019827 stem cell population maintenance IEA
 biological_processGO:0033962 cytoplasmic mRNA processing body assembly IDA
 biological_processGO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay TAS
 biological_processGO:0045665 negative regulation of neuron differentiation IEA
 cellular_componentGO:0000792 heterochromatin IEA
 cellular_componentGO:0000932 P-body IMP
 cellular_componentGO:0001520 outer dense fiber IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0010494 cytoplasmic stress granule IDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0016442 RISC complex IDA
 cellular_componentGO:0036464 cytoplasmic ribonucleoprotein granule IDA
 cellular_componentGO:0043186 P granule IEA
 cellular_componentGO:0097227 sperm annulus IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003724 RNA helicase activity TAS
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IBA
 molecular_functionGO:0004386 helicase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019904 protein domain specific binding IPI
 molecular_functionGO:0045296 cadherin binding IDA


Pathways (from Reactome)
Pathway description
mRNA decay by 5 to 3 exoribonuclease


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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