ENSDARG00000062049


Danio rerio

Features
Gene ID: ENSDARG00000062049
  
Biological name :hmha1b
  
Synonyms : histocompatibility (minor) HA-1 b / hmha1b
  
Possible biological names infered from orthology : ARHGAP45 / Mus musculus Rho GTPase activating protein 45 (Arhgap45), transcript variant 3, mRNA. / Q3TBD2 / Q92619 / Rho GTPase activating protein 45
  
Species: Danio rerio
  
Chr. number: 22
Strand: -1
Band:
Gene start: 17611836
Gene end: 17653143
  
Corresponding Affymetrix probe sets: Dr.6361.1.A1_at (Zebrafish Array)   XM_678493_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000083604
Ensembl peptide - ENSDARP00000114753
Ensembl peptide - ENSDARP00000145715
NCBI entrez gene - 555849     See in Manteia.
RefSeq - XM_678493
swissprot - F1Q6Y5
swissprot - F1QDJ8
ZFIN ID - ZDB-GENE-071213-2
Ensembl - ENSDARG00000062049
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ARHGAP45ENSGALG00000032469Gallus gallus
 Q92619ENSG00000180448Homo sapiens
 Q3TBD2ENSMUSG00000035697Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
hmha1a / histocompatibility (minor) HA-1 a / Q92619* / ARHGAP45* / Rho GTPase activating protein 45*ENSDARG0000005249660
arhgap29b / Rho GTPase activating protein 29b / Q52LW3* / Q8CGF1* / ARHGAP29* / Rho GTPase activating protein 29* / Mus musculus Rho GTPase activating protein 29 (Arhgap29), transcript vari...ENSDARG0000001774836
arhgap29a / Rho GTPase activating protein 29a / Q52LW3* / Q8CGF1* / ARHGAP29* / Rho GTPase activating protein 29* / Mus musculus Rho GTPase activating protein 29 (Arhgap29), transcript vari...ENSDARG0000002632935
si:ch73-243b8.4ENSDARG0000009517424
gmip / GEM interacting protein / Q6PGG2* / Q9P107*ENSDARG0000007724921
arhgap42a / Rho GTPase activating protein 42a / B2RQE8* / Q9H2Q1* / A6NI28* / ARHGAP42* / Rho GTPase activating protein 42*ENSDARG0000005661911
arhgap42b / Rho GTPase activating protein 42b / A6NI28* / Q9H2Q1* / ARHGAP42* / Rho GTPase activating protein 42*ENSDARG0000001065411
arhgap32a / Rho GTPase activating protein 32a / A7KAX9* / Q811P8* / ARHGAP32* / Rho GTPase activating protein 32*ENSDARG0000007533410
racgap1 / Rac GTPase activating protein 1 / Q9H0H5* / Q9WVM1*ENSDARG0000001546010
arhgap32b / Rho GTPase activating protein 32b / A7KAX9* / Q811P8* / ARHGAP32* / Rho GTPase activating protein 32*ENSDARG0000007418410
ophn1 / oligophrenin 1 / O60890* / Q99J31*ENSDARG0000003542010
arhgap10 / Rho GTPase activating protein 10 / A1A4S6* / Q6Y5D8*ENSDARG0000007832610
si:ch1073-416j23.1ENSDARG000000559349
arhgap33 / Rho GTPase activating protein 33 / O14559* / Q80YF9*ENSDARG000000113339
ralbp1 / ralA binding protein 1 / Q15311*ENSDARG000000786537
si:dkeyp-68b7.12 / Q7Z6I6* / ARHGAP30* / Rho GTPase activating protein 30*ENSDARG000000748466
arhgap31 / Rho GTPase activating protein 31 / A6X8Z5* / Q2M1Z3*ENSDARG000000594726


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR001060  FCH domain
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR008936  Rho GTPase activation protein
 IPR027267  AH/BAR domain superfamily
 IPR031160  F-BAR domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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