ENSMUSG00000035697


Mus musculus

Features
Gene ID: ENSMUSG00000035697
  
Biological name :Arhgap45
  
Synonyms : Arhgap45 / Mus musculus Rho GTPase activating protein 45 (Arhgap45), transcript variant 3, mRNA. / Q3TBD2
  
Possible biological names infered from orthology : Q92619 / Rho GTPase activating protein 45
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: C1
Gene start: 80016653
Gene end: 80031472
  
Corresponding Affymetrix probe sets: 10364650 (MoGene1.0st)   1428242_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000041019
Ensembl peptide - ENSMUSP00000097100
Ensembl peptide - ENSMUSP00000101012
NCBI entrez gene - 70719     See in Manteia.
MGI - MGI:1917969
RefSeq - XM_006514110
RefSeq - NM_001142701
RefSeq - NM_001347074
RefSeq - NM_027521
RefSeq - XM_006514108
RefSeq - XM_006514109
RefSeq Peptide - NP_001334003
RefSeq Peptide - NP_081797
RefSeq Peptide - NP_001136173
swissprot - G3X9Q3
swissprot - Q3TBD2
swissprot - D3Z7R7
Ensembl - ENSMUSG00000035697
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hmha1aENSDARG00000052496Danio rerio
 hmha1bENSDARG00000062049Danio rerio
 ARHGAP45ENSGALG00000032469Gallus gallus
 Q92619ENSG00000180448Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8CGF1 / Arhgap29 / Mus musculus Rho GTPase activating protein 29 (Arhgap29), transcript variant 2, mRNA. / Q52LW3* / Rho GTPase activating protein 29*ENSMUSG0000003983133
Gmip / Q6PGG2 / Gem-interacting protein / Q9P107*ENSMUSG0000003624627
Q80YF9 / Arhgap33 / Rho GTPase-activating protein 33 / O14559*ENSMUSG0000003688212
Q811P8 / Arhgap32 / Rho GTPase-activating protein 32 / A7KAX9*ENSMUSG0000004144412
Q6ZQ82 / Arhgap26 / Rho GTPase activating protein 26 / Q9UNA1*ENSMUSG0000003645212
Q9WVM1 / Racgap1 / Rac GTPase-activating protein 1 / Q9H0H5*ENSMUSG0000002301511
Ophn1 / Q99J31 / Oligophrenin-1 / O60890*ENSMUSG0000003121411
B2RQE8 / Arhgap42 / Rho GTPase activating protein 42 / A6NI28* / Q9H2Q1*ENSMUSG0000005073011
Q6Y5D8 / Arhgap10 / Rho GTPase-activating protein 10 / A1A4S6*ENSMUSG0000003714811
Q62172 / Ralbp1 / ralA binding protein 1 / Q15311*ENSMUSG000000240969
A6X8Z5 / Arhgap31 / Rho GTPase activating protein 31 / Q2M1Z3*ENSMUSG000000227998
Arhgap30 / Rho GTPase activating protein 30 / Q7Z6I6*ENSMUSG000000488657


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR001060  FCH domain
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR008936  Rho GTPase activation protein
 IPR027267  AH/BAR domain superfamily
 IPR031160  F-BAR domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0032587 ruffle membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr