ENSMUSG00000036452


Mus musculus

Features
Gene ID: ENSMUSG00000036452
  
Biological name :Arhgap26
  
Synonyms : Arhgap26 / Q6ZQ82 / Rho GTPase activating protein 26
  
Possible biological names infered from orthology : Q9UNA1
  
Species: Mus musculus
  
Chr. number: 18
Strand: 1
Band: B3
Gene start: 38601534
Gene end: 39376284
  
Corresponding Affymetrix probe sets: 10455249 (MoGene1.0st)   10455253 (MoGene1.0st)   10455259 (MoGene1.0st)   1430957_at (Mouse Genome 430 2.0 Array)   1435694_at (Mouse Genome 430 2.0 Array)   1440688_at (Mouse Genome 430 2.0 Array)   1444128_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000122371
Ensembl peptide - ENSMUSP00000121894
Ensembl peptide - ENSMUSP00000122448
Ensembl peptide - ENSMUSP00000141188
Ensembl peptide - ENSMUSP00000123145
Ensembl peptide - ENSMUSP00000095200
Ensembl peptide - ENSMUSP00000119865
Ensembl peptide - ENSMUSP00000121197
NCBI entrez gene - 71302     See in Manteia.
NCBI entrez gene - 545253     See in Manteia.
MGI - MGI:1918552
RefSeq - XM_006526268
RefSeq - XM_017317984
RefSeq - XM_017317985
RefSeq - XM_017317986
RefSeq - XM_017317987
RefSeq - XM_017317988
RefSeq - XM_017317989
RefSeq - XM_017317990
RefSeq - XM_006526267
RefSeq - XM_006526269
RefSeq - NM_001033789
RefSeq - NM_175164
RefSeq Peptide - NP_001028961
RefSeq Peptide - NP_780373
swissprot - Q6ZQ82
swissprot - D3Z1X5
swissprot - F6Q7M1
swissprot - F6XTB7
swissprot - F7D661
swissprot - A0A087WSU1
swissprot - Q3U860
swissprot - E9QAQ3
Ensembl - ENSMUSG00000036452
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q5ZMW5ENSGALG00000033938Gallus gallus
 Q9UNA1ENSG00000145819Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6Y5D8 / Arhgap10 / Rho GTPase-activating protein 10 / A1A4S6*ENSMUSG0000003714854
B2RQE8 / Arhgap42 / Rho GTPase activating protein 42 / A6NI28* / Q9H2Q1*ENSMUSG0000005073049
Ophn1 / Q99J31 / Oligophrenin-1 / O60890*ENSMUSG0000003121443
Q3TBD2 / Arhgap45 / Mus musculus Rho GTPase activating protein 45 (Arhgap45), transcript variant 3, mRNA. / Q92619* / Rho GTPase activating protein 45*ENSMUSG0000003569716
Q811P8 / Arhgap32 / Rho GTPase-activating protein 32 / A7KAX9*ENSMUSG0000004144416
Q8CGF1 / Arhgap29 / Mus musculus Rho GTPase activating protein 29 (Arhgap29), transcript variant 2, mRNA. / Q52LW3* / Rho GTPase activating protein 29*ENSMUSG0000003983115
Gmip / Q6PGG2 / Gem-interacting protein / Q9P107*ENSMUSG0000003624615
A6X8Z5 / Arhgap31 / Rho GTPase activating protein 31 / Q2M1Z3*ENSMUSG0000002279914
Q80YF9 / Arhgap33 / Rho GTPase-activating protein 33 / O14559*ENSMUSG0000003688213
Q62172 / Ralbp1 / ralA binding protein 1 / Q15311*ENSMUSG0000002409612
Arhgap30 / Rho GTPase activating protein 30 / Q7Z6I6*ENSMUSG0000004886511
Q9WVM1 / Racgap1 / Rac GTPase-activating protein 1 / Q9H0H5*ENSMUSG0000002301510


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR001452  SH3 domain
 IPR001849  Pleckstrin homology domain
 IPR008936  Rho GTPase activation protein
 IPR011993  PH-like domain superfamily
 IPR027267  AH/BAR domain superfamily
 IPR030061  Rho GTPase-activating protein 26
 IPR035481  GRAF, SH3 domain
 IPR035483  GRAF, BAR domain
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005543 phospholipid binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000750 abnormal muscle regeneration "inability or defects in ability to repair muscle after injuries" [J:42574]
Show

Allelic Composition: Fam208aMommeD20/Fam208aMommeD20
Genetic Background: FVB/NJ-Fam208aMommeD20

 MP:0002106 abnormal muscle physiology "anomolous function of the muscle, not due to an anatomical defect" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Fam208aMommeD20/Fam208aMommeD20
Genetic Background: FVB/NJ-Fam208aMommeD20

 MP:0009400 decreased skeletal muscle fiber size "decrease in the size of the large multinucleated cells that make up the skeletal muscles" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Fam208aMommeD20/Fam208aMommeD20
Genetic Background: FVB/NJ-Fam208aMommeD20

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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