ENSDARG00000062198


Danio rerio

Features
Gene ID: ENSDARG00000062198
  
Biological name :pcm1
  
Synonyms : pcm1 / pericentriolar material 1
  
Possible biological names infered from orthology : Q15154 / Q9R0L6
  
Species: Danio rerio
  
Chr. number: 1
Strand: 1
Band:
Gene start: 16621345
Gene end: 16654161
  
Corresponding Affymetrix probe sets: Dr.3482.2.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000124973
Ensembl peptide - ENSDARP00000136285
swissprot - A0A0R4IN23
swissprot - F8W5U4
ZFIN ID - ZDB-GENE-030131-428
Ensembl - ENSDARG00000062198
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PCM1ENSGALG00000013602Gallus gallus
 PCM1ENSG00000078674Homo sapiens
 Pcm1ENSMUSG00000031592Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR024138  Pericentriolar material 1 protein
 IPR031446  Pericentriolar material 1 protein, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0034454 microtubule anchoring at centrosome IEA
 biological_processGO:0060271 cilium assembly IEA
 biological_processGO:0071539 protein localization to centrosome IEA
 cellular_componentGO:0005813 centrosome IDA


Pathways (from Reactome)
Pathway description
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle cilium decreased length , abnormal
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 ZFA:0000008 brain brain hydrocephalic , abnormal
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 ZFA:0000051 otic vesicle otic vesicle has extra parts of type otolith , abnormal
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 ZFA:0000151 pronephros pronephros cilium decreased length , abnormal
pronephros cystic , abnormal
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 ZFA:0001094 whole organism whole organism anterior-posterior axis curved ventral , abnormal
whole organism anterior-posterior axis curved lateral , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr