ENSMUSG00000031592


Mus musculus

Features
Gene ID: ENSMUSG00000031592
  
Biological name :Pcm1
  
Synonyms : Pcm1 / pericentriolar material 1 / Q9R0L6
  
Possible biological names infered from orthology : Q15154
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: A4
Gene start: 41239752
Gene end: 41332344
  
Corresponding Affymetrix probe sets: 10571474 (MoGene1.0st)   1418524_at (Mouse Genome 430 2.0 Array)   1418525_at (Mouse Genome 430 2.0 Array)   1431287_at (Mouse Genome 430 2.0 Array)   1436908_at (Mouse Genome 430 2.0 Array)   1449120_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000039709
Ensembl peptide - ENSMUSP00000147887
Ensembl peptide - ENSMUSP00000148180
NCBI entrez gene - 18536     See in Manteia.
MGI - MGI:1277958
RefSeq - XM_017312615
RefSeq - NM_023662
RefSeq - XM_006509302
RefSeq - XM_006509304
RefSeq - XM_011242179
RefSeq - XM_006509298
RefSeq - XM_006509299
RefSeq - XM_006509300
RefSeq - XM_006509301
RefSeq Peptide - NP_076151
swissprot - Q9R0L6
swissprot - A0A1B0GT33
Ensembl - ENSMUSG00000031592
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pcm1ENSDARG00000062198Danio rerio
 PCM1ENSGALG00000013602Gallus gallus
 PCM1ENSG00000078674Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR024138  Pericentriolar material 1 protein
 IPR031446  Pericentriolar material 1 protein, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001764 neuron migration IMP
 biological_processGO:0007098 centrosome cycle IBA
 biological_processGO:0022027 interkinetic nuclear migration IMP
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0031122 cytoplasmic microtubule organization ISO
 biological_processGO:0034453 microtubule anchoring IMP
 biological_processGO:0034454 microtubule anchoring at centrosome IMP
 biological_processGO:0035176 social behavior IMP
 biological_processGO:0035735 intraciliary transport involved in cilium assembly ISO
 biological_processGO:0050768 negative regulation of neurogenesis IMP
 biological_processGO:0060271 cilium assembly IBA
 biological_processGO:0071539 protein localization to centrosome ISO
 biological_processGO:0090316 positive regulation of intracellular protein transport ISO
 biological_processGO:0097150 neuronal stem cell population maintenance IMP
 biological_processGO:1905515 non-motile cilium assembly ISO
 cellular_componentGO:0000242 pericentriolar material IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005814 centriole IDA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0031965 nuclear membrane ISO
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0034451 centriolar satellite ISO
 cellular_componentGO:0035869 ciliary transition zone ISO
 cellular_componentGO:0036064 ciliary basal body IDA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0045177 apical part of cell IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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