ENSDARG00000063433


Danio rerio

Features
Gene ID: ENSDARG00000063433
  
Biological name :atp2b2
  
Synonyms : atp2b2 / ATPase plasma membrane Ca2+ transporting 2
  
Possible biological names infered from orthology : Plasma membrane calcium-transporting ATPase 2 / Q01814 / Q9R0K7
  
Species: Danio rerio
  
Chr. number: 11
Strand: -1
Band:
Gene start: 1148701
Gene end: 1291012
  
Corresponding Affymetrix probe sets: Dr.11302.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000129987
NCBI entrez gene - 557430     See in Manteia.
RefSeq - NM_001123238
RefSeq Peptide - NP_001116710
swissprot - F1RC03
ZFIN ID - ZDB-GENE-061016-1
Ensembl - ENSDARG00000063433
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ATP2B2ENSGALG00000030908Gallus gallus
 ATP2B2ENSG00000157087Homo sapiens
 Atp2b2ENSMUSG00000030302Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
atp2b1a / ATPase plasma membrane Ca2+ transporting 1a / ATP2B1* / G5E829* / P20020* / ATPase plasma membrane Ca2+ transporting 1* / Plasma membrane calcium-transporting ATPase 1 *ENSDARG0000001268476
atp2b1b / ATPase plasma membrane Ca2+ transporting 1b / ATP2B1* / G5E829* / P20020* / ATPase plasma membrane Ca2+ transporting 1* / Plasma membrane calcium-transporting ATPase 1 *ENSDARG0000000778874
atp2b3b / ATPase plasma membrane Ca2+ transporting 3b / Q16720* / ATP2B3* / ATPase plasma membrane Ca2+ transporting 3* / ATPase, Ca++ transporting, plasma membrane 3*ENSDARG0000002344573
atp2b3a / ATPase plasma membrane Ca2+ transporting 3a / Q16720* / ATP2B3* / ATPase plasma membrane Ca2+ transporting 3* / ATPase, Ca++ transporting, plasma membrane 3*ENSDARG0000004347473
atp2b4 / atp2b2 / ATPase plasma membrane Ca2+ transporting 2 / P23634* / Q6Q477* / ATPase plasma membrane Ca2+ transporting 4* / Plasma membrane calcium-transporting ATPase 4 *ENSDARG0000004490272


Protein motifs (from Interpro)
Interpro ID Name
 IPR001757  P-type ATPase
 IPR004014  Cation-transporting P-type ATPase, N-terminal
 IPR006068  Cation-transporting P-type ATPase, C-terminal
 IPR006408  P-type ATPase, subfamily IIB
 IPR008250  P-type ATPase, A domain superfamily
 IPR018303  P-type ATPase, phosphorylation site
 IPR022141  Plasma membrane calcium transporting P-type ATPase, C-terminal
 IPR023214  HAD superfamily
 IPR023298  P-type ATPase, transmembrane domain superfamily
 IPR023299  P-type ATPase, cytoplasmic domain N


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0006874 cellular calcium ion homeostasis IBA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 biological_processGO:0099132 ATP hydrolysis coupled cation transmembrane transport IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005388 calcium-transporting ATPase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0030165 PDZ domain binding IBA


Pathways (from Reactome)
Pathway description
Reduction of cytosolic Ca++ levels
Ion homeostasis
Ion transport by P-type ATPases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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