MP:0000026 | abnormal inner ear morphology | "malformation or malfunction of any components of the labyrinth, including the semicircular canals, vestibule and cochlea" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:1776] |
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Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
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MP:0000032 | cochlear degeneration | "a retrogressive impairment of function or destruction of the part of the inner ear forms the anterior part of the labyrinth, is conical, and is concerned with hearing" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Atp2b2wri/Atp2b2wri Genetic Background: involves: BALB/cAnN
Allelic Composition: Atp2b2wri/Atp2b2+ Genetic Background: involves: BALB/cAnN
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MP:0000034 | abnormal vestibule morphology | "malformed cavity between the semicircular canals and the cochlea of the inner ear" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:1776] |
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Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
Allelic Composition: Atp2b2Elfin/Atp2b2Elfin Genetic Background: involves: C3H/HeJ * C57BL/6J
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MP:0000042 | abnormal organ of Corti | "abnormalities associated with the highly specialized epithelium in the floor of the ductus cochlearis; also referred to a spiral organ (organum spirale), or acoustic papilla" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
Allelic Composition: Atp2b2tm1Ges/Atp2b2+ Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
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MP:0000043 | organ of Corti degeneration | "a retrogressive impairment of function or destruction of the highly specialized epithelium in the floor of the ductus cochlearis" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Atp2b2Obv/Atp2b2Obv Genetic Background: C3HeB/FeJ-Atp2b2Obv
Allelic Composition: Atp2b2Elfin/Atp2b2Elfin Genetic Background: involves: C3H/HeJ * C57BL/6J
Allelic Composition: Atp2b2Elfin/Atp2b2+ Genetic Background: involves: C3H/HeJ * C57BL/6J
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MP:0000313 | abnormal cell death | "anomalous cessation of function at the cellular level" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Timp3tm1Rkho/Timp3tm1Rkho,Tnftm1Gkl/Tnftm1Gkl Genetic Background: involves: 129 * 129S/SvEv * C57BL/6
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MP:0000745 | tremors | "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Ltatm1Tab/Ltatm1Tab Genetic Background: either: (involves: 129S2/SvPas * C57BL/6J) or (involves: 129S2/SvPas * CF-1)
Allelic Composition: Atp2b2dfw-2J/Atp2b2dfw-2J Genetic Background: CByJ.A-Atp2b2dfw-2J/J
Allelic Composition: Atp2b2m1Mae/Atp2b2m1Mae,Ppargtm2Mae/Ppargtm2Mae Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Atp2b2jog/Atp2b2jog Genetic Background: involves: C57BL/6 * DSO
Allelic Composition: Atp2b2wri/Atp2b2wri Genetic Background: involves: BALB/cAnN
Allelic Composition: Atp2b2m1Btlr/Atp2b2m1Btlr Genetic Background: C57BL/6J-Atp2b2m1Btlr
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MP:0000788 | abnormal cerebral cortex morphology | "malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857] |
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Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
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MP:0000849 | abnormal cerebellum morphology | "any malformation or absence of the part of the metencephalon that lies in the posterior cranial fossa dorsal to the pons and medulla that is concerned with the coordination of movement and learning of motor skills" [J:50311, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
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MP:0000852 | small cerebellum | "reduced size of cerebellum" [MGI:CLS, J:17203, J:67524] |
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Allelic Composition: Atp2b2jog/Atp2b2jog Genetic Background: involves: C57BL/6 * DSO
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MP:0000879 | increased Purkinje cell number | "greater than normal number of neuronal cells that are located in the interface of the molecular and granular layers of the cerebellar cortex" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
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MP:0000890 | thin cerebellar molecular layer | "reduced width of the outer of the three cortical layers of the cerebellum" [J:46854] |
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Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
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MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
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Allelic Composition: Timp3tm1Rkho/Timp3tm1Rkho,Tnftm1Gkl/Tnftm1Gkl Genetic Background: involves: 129 * 129S/SvEv * C57BL/6
Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
Allelic Composition: Atp2b2Obv/Atp2b2Obv Genetic Background: C3HeB/FeJ-Atp2b2Obv
Allelic Composition: Atp2b2Elfin/Atp2b2Elfin Genetic Background: involves: C3H/HeJ * C57BL/6J
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MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
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Allelic Composition: Myd88poc/Myd88poc Genetic Background: C57BL/6-Myd88poc
Allelic Composition: Atp2b2Obv/Atp2b2Obv Genetic Background: C3HeB/FeJ-Atp2b2Obv
Allelic Composition: Atp2b2Tmy/Atp2b2Tmy Genetic Background: involves: BALB/c * C3H/HeH
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MP:0001393 | ataxia | "inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231] |
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Allelic Composition: Atp2b2dfw-2J/Atp2b2dfw-2J Genetic Background: CByJ.A-Atp2b2dfw-2J/J
Allelic Composition: Atp2b2m1Mae/Atp2b2m1Mae,Ppargtm2Mae/Ppargtm2Mae Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Atp2b2jog/Atp2b2jog Genetic Background: involves: C57BL/6 * DSO
Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
Allelic Composition: Atp2b2Obv/Atp2b2Obv Genetic Background: C3HeB/FeJ-Atp2b2Obv
Allelic Composition: Atp2b2Tmy/Atp2b2Tmy Genetic Background: involves: BALB/c * C3H/HeH
Allelic Composition: Atp2b2Elfin/Atp2b2Elfin Genetic Background: involves: C3H/HeJ * C57BL/6J
Allelic Composition: Atp2b2m1Btlr/Atp2b2m1Btlr Genetic Background: C57BL/6J-Atp2b2m1Btlr
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MP:0001394 | circling | "repeated, compulsive movement in a circle; often associated with inner ear defects" [MGI:CLS, J:61295] |
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Allelic Composition: Atp2b2Obv/Atp2b2Obv Genetic Background: C3HeB/FeJ-Atp2b2Obv
Allelic Composition: Atp2b2dfw-i5/Atp2b2dfw-i5 Genetic Background: involves: C57BL/6J * CBA/CaJ * DBA/2J
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MP:0001405 | impaired coordination | "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Atp2b2dfw-i5/Atp2b2dfw-i5 Genetic Background: involves: C57BL/6J * CBA/CaJ * DBA/2J
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MP:0001406 | abnormal gait | "unusual or distinctive way of walking" [J:65038] |
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Allelic Composition: Ap3b1pe-14J/Ap3b1pe-14J Genetic Background: B6;129S2 Seletm1Hyn-Ap3b1pe-14J/GrsrJ
Allelic Composition: Atp2b2dfw-2J/Atp2b2dfw-2J Genetic Background: CByJ.A-Atp2b2dfw-2J/J
Allelic Composition: Atp2b2m1Mae/Atp2b2m1Mae,Ppargtm2Mae/Ppargtm2Mae Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Atp2b2wri/Atp2b2wri Genetic Background: involves: BALB/cAnN
Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
Allelic Composition: Atp2b2Tmy/Atp2b2Tmy Genetic Background: involves: BALB/c * C3H/HeH
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MP:0001408 | stereotypic behavior | "repetitive, invariant, perseverative motor patterns that do not appear to be purposeful" [What s wrong with my mouse?:ISBN 0-471-31639-3] |
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Allelic Composition: Atp2b2dfw-i5/Atp2b2dfw-i5 Genetic Background: involves: C57BL/6J * CBA/CaJ * DBA/2J
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MP:0001410 | head bobbing | "compulsive up and down movement of the head" [J:17123] |
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Allelic Composition: Ap3b1pe-14J/Ap3b1pe-14J Genetic Background: B6;129S2 Seletm1Hyn-Ap3b1pe-14J/GrsrJ
Allelic Composition: Atp2b2dfw-2J/Atp2b2dfw-2J Genetic Background: CByJ.A-Atp2b2dfw-2J/J
Allelic Composition: Atp2b2m1Mae/Atp2b2m1Mae,Ppargtm2Mae/Ppargtm2Mae Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Atp2b2m1Btlr/Atp2b2m1Btlr Genetic Background: C57BL/6J-Atp2b2m1Btlr
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MP:0001489 | decreased startle reflex | "greater threshold or less severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, What s Wrong With My Mouse?:ISBN 0-471-31639-3] |
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Allelic Composition: Atp2b2m1Mae/Atp2b2m1Mae,Ppargtm2Mae/Ppargtm2Mae Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Atp2b2Deaf11/Atp2b2Deaf11 Genetic Background: BALB/c-Atp2b2Deaf11
Allelic Composition: Atp2b2Deaf11/Atp2b2+ Genetic Background: BALB/c-Atp2b2Deaf11
Allelic Composition: Atp2b2Deaf13/Atp2b2+ Genetic Background: BALB/c-Atp2b2Deaf13
Allelic Composition: Atp2b2Deaf13/Atp2b2Deaf13 Genetic Background: BALB/c-Atp2b2Deaf13
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MP:0001490 | abnormal vibrissae reflex | "animals do not change position in response to stimulation of the whiskers" [J:17194] |
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Allelic Composition: Myd88poc/Myd88poc Genetic Background: C57BL/6-Myd88poc
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MP:0001504 | abnormal posture | "atypical position of the limbs or carriage of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:18984] |
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Allelic Composition: Timp3tm1Rkho/Timp3tm1Rkho,Tnftm1Gkl/Tnftm1Gkl Genetic Background: involves: 129 * 129S/SvEv * C57BL/6
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MP:0001513 | limb grasping | "mice clasp front and/or hind feet almost immediately upon being lifted by tail" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator] |
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Allelic Composition: Timp3tm1Rkho/Timp3tm1Rkho,Tnftm1Gkl/Tnftm1Gkl Genetic Background: involves: 129 * 129S/SvEv * C57BL/6
Allelic Composition: Atp2b2Elfin/Atp2b2Elfin Genetic Background: involves: C3H/HeJ * C57BL/6J
Allelic Composition: Atp2b2m1Btlr/Atp2b2m1Btlr Genetic Background: C57BL/6J-Atp2b2m1Btlr
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MP:0001516 | abnormal motor coordination/ balance | "altered ability of an animal to maintain skillful and effective interaction of movements or maintenance of equilibrium" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ltatm1Tab/Ltatm1Tab Genetic Background: either: (involves: 129S2/SvPas * C57BL/6J) or (involves: 129S2/SvPas * CF-1)
Allelic Composition: Atp2b2m1Mae/Atp2b2m1Mae,Ppargtm2Mae/Ppargtm2Mae Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Atp2b2wri/Atp2b2wri Genetic Background: involves: BALB/cAnN
Allelic Composition: Atp2b2dfw-i5/Atp2b2dfw-i5 Genetic Background: involves: C57BL/6J * CBA/CaJ * DBA/2J
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MP:0001522 | impaired swimming | "reduced ability or inability to swim" [J:45446, J:39081] |
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Allelic Composition: Atp2b2dfw-2J/Atp2b2dfw-2J Genetic Background: CByJ.A-Atp2b2dfw-2J/J
Allelic Composition: Atp2b2dfw-2J/Atp2b2dfw-2J Genetic Background: CBA.Cg-Atp2b2dfw-2J
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MP:0001523 | impaired righting response | "reduced ability or greater amount of time needed to recover from supine position" [J:25565] |
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Allelic Composition: Atp2b2m1Mae/Atp2b2m1Mae,Ppargtm2Mae/Ppargtm2Mae Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
Allelic Composition: Atp2b2Obv/Atp2b2Obv Genetic Background: C3HeB/FeJ-Atp2b2Obv
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MP:0001524 | impaired limb coordination | "reduced ability to organize limb movements to execute complex maneuvers, such as walking" [J:64962, MGI:CLS, J:17123] |
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Allelic Composition: Atp2b2jog/Atp2b2jog Genetic Background: involves: C57BL/6 * DSO
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MP:0001525 | impaired balance | "reduced ability of an animal to maintain equilibrium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:64962, J:17123] |
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Allelic Composition: Atp2b2m1Mae/Atp2b2m1Mae,Ppargtm2Mae/Ppargtm2Mae Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
Allelic Composition: Atp2b2Obv/Atp2b2Obv Genetic Background: C3HeB/FeJ-Atp2b2Obv
Allelic Composition: Atp2b2Elfin/Atp2b2Elfin Genetic Background: involves: C3H/HeJ * C57BL/6J
Allelic Composition: Atp2b2dfw-i5/Atp2b2dfw-i5 Genetic Background: involves: C57BL/6J * CBA/CaJ * DBA/2J
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MP:0001732 | postnatal growth retardation | "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Atp2b2m1Mae/Atp2b2m1Mae,Ppargtm2Mae/Ppargtm2Mae Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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MP:0001924 | infertility | "inability to produce live offspring" [J:47225] |
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Allelic Composition: Atp2b2dfw-2J/Atp2b2dfw-2J Genetic Background: CByJ.A-Atp2b2dfw-2J/J
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MP:0001961 | abnormal reflex | "anomalies in an involuntary response to a peripheral stimulus" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Atp2b2dfw-2J/Atp2b2dfw-2J Genetic Background: CByJ.A-Atp2b2dfw-2J/J
Allelic Composition: Atp2b2m1Mae/Atp2b2m1Mae,Ppargtm2Mae/Ppargtm2Mae Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
Allelic Composition: Atp2b2Obv/Atp2b2Obv Genetic Background: C3HeB/FeJ-Atp2b2Obv
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MP:0001963 | abnormal hearing | "anomaly in the ability to receive auditory stimuli" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Atp2b2dfw-i5/Atp2b2dfw-i5 Genetic Background: involves: C57BL/6J * CBA/CaJ * DBA/2J
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MP:0001967 | deafness | "inability to hear" [J:57651] |
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Allelic Composition: Ltatm1Tab/Ltatm1Tab Genetic Background: either: (involves: 129S2/SvPas * C57BL/6J) or (involves: 129S2/SvPas * CF-1)
Allelic Composition: Atp2b2dfw/Atp2b2dfw Genetic Background: C3H/HeJ-Atp2b2dfw/J
Allelic Composition: Atp2b2dfw-2J/Atp2b2dfw-2J Genetic Background: CByJ.A-Atp2b2dfw-2J/J
Allelic Composition: Atp2b2dfw-2J/Atp2b2+ Genetic Background: CByJ.A-Atp2b2dfw-2J/J
Allelic Composition: Atp2b2wri/Atp2b2wri Genetic Background: involves: BALB/cAnN
Allelic Composition: Atp2b2wri/Atp2b2+ Genetic Background: involves: BALB/cAnN
Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
Allelic Composition: Atp2b2dfw-2J/Atp2b2+,Cdh23ahl/Cdh23ahl Genetic Background: involves: CAST/Ei * BALB/cByJ
Allelic Composition: Atp2b2dfw-2J/Atp2b2+,Cdh23ahl/Cdh23ahl Genetic Background: involves: BALB/cByJ * MOLF
Allelic Composition: Atp2b2Obv/Atp2b2+ Genetic Background: C3HeB/FeJ-Atp2b2Obv
Allelic Composition: Atp2b2Obv/Atp2b2Obv Genetic Background: C3HeB/FeJ-Atp2b2Obv
Allelic Composition: Atp2b2Tmy/Atp2b2+ Genetic Background: involves: BALB/c * C3H/HeH
Allelic Composition: Atp2b2Tmy/Atp2b2Tmy Genetic Background: involves: BALB/c * C3H/HeH
Allelic Composition: Atp2b2dfw-i5/Atp2b2dfw-i5 Genetic Background: involves: C57BL/6J * CBA/CaJ * DBA/2J
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MP:0001993 | abnormal blinking | |
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Allelic Composition: Atp2b2m1Mae/Atp2b2m1Mae,Ppargtm2Mae/Ppargtm2Mae Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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MP:0002855 | abnormal cochlear ganglion morphology | "malformation, malfunction or absence of the group of nerve cell bodies that conveys auditory sensation from the organ of Corti to the hindbrain and resides on the cochlear part of the vestibulocochlear nerve (eighth cranial nerve)" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Atp2b2dfw/Atp2b2dfw Genetic Background: C3H/HeJ-Atp2b2dfw/J
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MP:0002857 | cochlear ganglion degeneration | "loss of neural cell bodies in the group of nerve cell bodies that conveys auditory sensation from the organ of Corti to the hindbrain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Atp2b2dfw/Atp2b2dfw Genetic Background: C3H/HeJ-Atp2b2dfw/J
Allelic Composition: Atp2b2wri/Atp2b2wri Genetic Background: involves: BALB/cAnN
Allelic Composition: Atp2b2wri/Atp2b2+ Genetic Background: involves: BALB/cAnN
Allelic Composition: Atp2b2Elfin/Atp2b2+ Genetic Background: involves: C3H/HeJ * C57BL/6J
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MP:0002978 | absent otoliths | "absence of the crystalline calciferous particles adhering to the otolithic membrane" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
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MP:0002980 | abnormal postural reflex | "failure to respond with the normal extension of legs to maintain balance when the cage is tilted" [smb:Susan M. Bello , Mouse Genome Informatics Curator, J:88306] |
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Allelic Composition: Atp2b2wri/Atp2b2wri Genetic Background: involves: BALB/cAnN
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MP:0003088 | abnormal prepulse inhibition | "increase or decrease in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [smb:Susan M. Bello, Mouse Genome Informatics Curator, J:91131] |
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Allelic Composition: Atp2b2m1Mae/Atp2b2m1Mae,Ppargtm2Mae/Ppargtm2Mae Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Atp2b2m1Mae/Atp2b2+,Ppargtm2Mae/Pparg+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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MP:0003151 | absent tunnel of Corti | "complete absence of the triangular, fluid-filled space normally found between the inner and outer rows of supporting pillar cells in the organ of Corti" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:32991] |
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Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
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MP:0003894 | abnormal Purkinje cell innervation | "malformation or absence of the supply of nerve fibers that connect to the Purkinje cells" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Atp2b2wri/Atp2b2wri Genetic Background: involves: BALB/cAnN
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MP:0004098 | abnormal granule neuron | "any structural anomaly of the small neurons of the granule cell layer that send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
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MP:0004231 | abnormal calcium ion homeostasis | "anomaly in the processes involved in the maintenance of an internal equilibrium of calcium ions within the body or between a cell and its external environment" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2dfw/Atp2b2dfw Genetic Background: C3H/HeJ-Atp2b2dfw/J
Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
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MP:0004301 | absent supporting cells | "absence of the highly differentiated epithelial cells with distinctive morphological features that surround all hair cells in the organ of Corti" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
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MP:0004312 | absent pillar cells | "absence of the supporting cells that form the inner and outer walls of the tunnel in the organ of Corti" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
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MP:0004325 | absent vestibular hair cells | "absence of the sensory epithelial cells of the maculae and cristae of the membranous labyrinth of the inner ear which are normally in synaptic contact with the vestibular nerve" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2Elfin/Atp2b2Elfin Genetic Background: involves: C3H/HeJ * C57BL/6J
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MP:0004329 | saccular degeneration | "degeneration or loss of the smaller of the two sacs in the vestibule" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2wri/Atp2b2wri Genetic Background: involves: BALB/cAnN
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MP:0004362 | cochlear hair cell degeneration | "degeneration or loss of the sensory epithelial cells of the cochlea; these cells are in synaptic contact with the auditory nerve" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2dfw/Atp2b2dfw Genetic Background: C3H/HeJ-Atp2b2dfw/J
Allelic Composition: Atp2b2Obv/Atp2b2+ Genetic Background: C3HeB/FeJ-Atp2b2Obv
Allelic Composition: Atp2b2Obv/Atp2b2Obv Genetic Background: C3HeB/FeJ-Atp2b2Obv
Allelic Composition: Atp2b2Deaf11/Atp2b2Deaf11 Genetic Background: BALB/c-Atp2b2Deaf11
Allelic Composition: Atp2b2Deaf13/Atp2b2Deaf13 Genetic Background: BALB/c-Atp2b2Deaf13
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MP:0004398 | cochlear inner hair cell degeneration | "degeneration or loss of the single row of flask-shaped inner hair sensory cells of the organ of Corti" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2Obv/Atp2b2+ Genetic Background: C3HeB/FeJ-Atp2b2Obv
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MP:0004404 | cochlear outer hair cell degeneration | "degeneration or loss of the columnar outer hair sensory cells of the organ of Corti" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2dfw/Atp2b2dfw Genetic Background: C3H/HeJ-Atp2b2dfw/J
Allelic Composition: Atp2b2wri/Atp2b2wri Genetic Background: involves: BALB/cAnN
Allelic Composition: Atp2b2Obv/Atp2b2+ Genetic Background: C3HeB/FeJ-Atp2b2Obv
Allelic Composition: Atp2b2Elfin/Atp2b2+ Genetic Background: involves: C3H/HeJ * C57BL/6J
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MP:0004405 | absent cochlear hair cells | "absence of the sensory epithelial cells of the cochlea; these cells are normally in synaptic contact with the auditory nerve" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
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MP:0004408 | decreased cochlear hair cell number | "decreased number of the sensory epithelial cells of the cochlea, which are normally in synaptic contact with the auditory nerve" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
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MP:0004412 | abnormal cochlear microphonics | "anomalous bioelectric potentials produced by the hair cells of the organ of Corti in response to sound; the cochlear microphonic (CM) is an electric response dominated by OHC receptor potentials from the basal turn of the cochlea and provides a measure of transducer function in OHCs; in an active ear, CM waveforms show post-stimulus ringing (i.e. a cochlear echo) whereas in a passive ear system, CM decays at the cessation of the tone burst" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2dfw/Atp2b2dfw Genetic Background: C3H/HeJ-Atp2b2dfw/J
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MP:0004415 | abnormal cochlear nerve compound action potential | "anomaly in the combined potentials resulting from activation of the auditory division of the eighth cranial nerve; these potentials represent the summed activity of multiple cochlear afferent fibers discharging synchronously and thus assess the combined functional state of OHCs, IHCs, and their primary afferent innervation" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2dfw/Atp2b2dfw Genetic Background: C3H/HeJ-Atp2b2dfw/J
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MP:0004431 | abnormal hair cell mechanoelectric transduction | "anomalous conversion of mechanical energy into electric(al) energy by sensory cells, such as auditory and vestibular hair cells, required for auditory sensation" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2dfw/Atp2b2dfw Genetic Background: C3H/HeJ-Atp2b2dfw/J
Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
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MP:0004432 | abnormal cochlear hair cell physiology | "anomalies in processes pertinent to the integrated function of cochlear hair cells i.e. the sensory cells in the spiral organ which are in synaptic contact with sensory as well as efferent fibers of the cochlear (auditory) nerve " [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2dfw/Atp2b2dfw Genetic Background: C3H/HeJ-Atp2b2dfw/J
Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
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MP:0004438 | abnormal vestibular hair cell physiology | "anomalies in processes pertinent to the integrated function of the sensory epithelium of the maculae and cristae in the membranous labyrinth of the inner ear" [J:100987, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2dfw/Atp2b2dfw Genetic Background: C3H/HeJ-Atp2b2dfw/J
Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
Allelic Composition: Atp2b2Obv/Atp2b2+ Genetic Background: C3HeB/FeJ-Atp2b2Obv
Allelic Composition: Atp2b2Obv/Atp2b2Obv Genetic Background: C3HeB/FeJ-Atp2b2Obv
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MP:0004497 | decreased supporting cell number | "decreased number of the highly differentiated epithelial cells with distinctive morphological features which surround the hair cells in the organ of Corti" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
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MP:0004521 | abnormal cochlear hair cell stereociliary bundle morphology | "any structural anomaly or disruption of the typical pattern of arrangement of mechanosensitive hair bundles which are composed of thick long microvilli (stereocilia) and are located at the apical end of cochlear inner and outer hair cells" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2dfw-i5/Atp2b2dfw-i5 Genetic Background: involves: C57BL/6J * CBA/CaJ * DBA/2J
Allelic Composition: Atp2b2dfw-i5/Atp2b2+ Genetic Background: involves: C57BL/6J * CBA/CaJ * DBA/2J
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MP:0004527 | abnormal outer hair cell stereociliary bundle morphology | "any structural anomaly or disruption of the typical V or W-like pattern of arrangement of mechanosensitive hair bundles located at the apical end of cochlear OHCs; each hair bundle is normally composed of ~100 nonmotile, actin-filled microvilli (stereocilia) arranged in rows of increasing height and coupled to one another by morphologically distinct links: tip links, horizontal top connectors, shaft connectors, and ankle links; most hair bundles also possess a single motile kinocilium immediately adjacent to the tallest (outermost) row of stereocilia; a fifth link type, the kinocilial link, connects the kinocilium to its neighboring stereocilia" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2Elfin/Atp2b2+ Genetic Background: involves: C3H/HeJ * C57BL/6J
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MP:0004530 | absent outer hair cell stereocilia | "complete absence of the nonmotile, actin-filled specialized microvilli (stereocilia) which are normally arrayed on cochlear outer hair cells" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2dfw/Atp2b2dfw Genetic Background: C3H/HeJ-Atp2b2dfw/J
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MP:0004586 | pillar cell degeneration | "degeneration or loss of the supporting cells that form the inner and outer walls of the tunnel in the organ of Corti" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2Obv/Atp2b2Obv Genetic Background: C3HeB/FeJ-Atp2b2Obv
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MP:0004597 | increased susceptibility to noise-induced hearing loss | "greater than normal reduction in hearing sensitivity following exposure to acute noise that is injurious to the cochlea" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2tm1Ges/Atp2b2+ Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss * C3H/HeJ
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MP:0004631 | abnormal auditory cortex morphology | "any structural abnormality in the region of the cerebral cortex that receives the auditory radiation from the medial geniculate body, a thalamic cell group receiving auditory input from the cochlear nuclei in the rhombencephalon and is responsible for processing of auditory (sound) information" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
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MP:0004716 | abnormal cochlear nerve morphology | "any structural abnormality in the part of the vestibulocochlear nerve [CN VIII] peripheral to the cochlear root; composed of the central nerve processes of the bipolar neurons of the spiral ganglion, which have their peripheral processes on the four rows of neuroepithelial cells (hair cells) of the spiral organ" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
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MP:0004736 | abnormal distortion product otoacoustic emission | "any abnormality in the sound produced by the cochlea in response to stimulation with 2 simultaneous tones of different frequencies; this measurement is particularly useful in assessing the functional state of OHCs" [eMedicine:http://www.emedicine.com/ent/topic372.htm, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2dfw/Atp2b2dfw Genetic Background: C3H/HeJ-Atp2b2dfw/J
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MP:0004737 | absent distortion product otoacoustic emissions | "failure to create mechanical distortions in the inner ear when two primary tones are presented, indicating failure of outer hair cells to amplify basilar membrane motion" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2dfw/Atp2b2dfw Genetic Background: C3H/HeJ-Atp2b2dfw/J
Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
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MP:0004738 | abnormal brainstem auditory evoked potential | "anomaly in the electrical activity generated in response to short tone bursts; may be used to evaluate sensorineural hearing function" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ltatm1Tab/Ltatm1Tab Genetic Background: either: (involves: 129S2/SvPas * C57BL/6J) or (involves: 129S2/SvPas * CF-1)
Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
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MP:0004740 | sensorineural hearing loss | "a form of progressive hearing loss due to a lesion of the auditory division of cranial nerve VIII or the inner ear" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
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MP:0004742 | abnormal vestibular system physiology | "any functional anomaly of the sensory system responsible for the sense of head position and movement of the body through space; such anomalies may include impaired balance, dizziness, poor regulation of postural muscle tone and inability to detect quick movements of the head " [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2Obv/Atp2b2Obv Genetic Background: C3HeB/FeJ-Atp2b2Obv
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MP:0004748 | increased susceptibility to age-related hearing loss | "greater than normal loss of hearing associated with advancing age, manifest as reduced ability to perceive or discriminate sounds; the pattern and age of onset vary" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2dfw-2J/Atp2b2+ Genetic Background: CByJ.A-Atp2b2dfw-2J/J
Allelic Composition: Atp2b2tm1Ges/Atp2b2+ Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss * C3H/HeJ
Allelic Composition: Atp2b2dfw-2J/Atp2b2+,Cdh23ahl/Cdh23ahl Genetic Background: involves: CAST/Ei * BALB/cByJ
Allelic Composition: Atp2b2Tmy/Atp2b2+ Genetic Background: involves: BALB/c * C3H/HeH
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MP:0004750 | syndromic hearing loss | "a form of progressive hearing loss that is usually associated with malformations of the external ear and other inherited signs and symptoms " [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2Tmy/Atp2b2+ Genetic Background: involves: BALB/c * C3H/HeH
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MP:0004813 | absent linear vestibular evoked potential | "absence of the biphasic response elicited by linear acceleration transients (usually jerk pulses to an animal s head)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2dfw-2J/Atp2b2dfw-2J Genetic Background: CByJ.A-Atp2b2dfw-2J/J
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MP:0004814 | reduced linear vestibular evoked potential | "reduction of the biphasic response elicited by linear acceleration transients (usually jerk pulses to an animal s head)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2dfw-2J/Atp2b2+ Genetic Background: CByJ.A-Atp2b2dfw-2J/J
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MP:0005202 | lethargy | "mild impairment of consciousness resulting in reduced alertness and awareness; ultimately due to generalized brain dysfunction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Atp2b2dfw-2J/Atp2b2dfw-2J Genetic Background: CByJ.A-Atp2b2dfw-2J/J
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MP:0005307 | head tossing | "compulsive flailing of the head in multiple directions" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Atp2b2Obv/Atp2b2Obv Genetic Background: C3HeB/FeJ-Atp2b2Obv
Allelic Composition: Atp2b2dfw-i5/Atp2b2dfw-i5 Genetic Background: involves: C57BL/6J * CBA/CaJ * DBA/2J
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MP:0006089 | abnormal saccule morphology | "malformation in the smaller of the two sacs in the vestibule" [smb:Susan M Bello, Mouse Genome Informatics Curator, Taber s Cyclopedic Medical Dictionary:19th edition: ISBN N 0-8036-0655-99, J:92940] |
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Allelic Composition: Atp2b2wri/Atp2b2wri Genetic Background: involves: BALB/cAnN
Allelic Composition: Atp2b2Elfin/Atp2b2Elfin Genetic Background: involves: C3H/HeJ * C57BL/6J
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MP:0006325 | impaired hearing | "reduced ability to percieve auditory stimuli" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2m1Mae/Atp2b2m1Mae,Ppargtm2Mae/Ppargtm2Mae Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Atp2b2m1Mae/Atp2b2+,Ppargtm2Mae/Pparg+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Atp2b2tm1Ges/Atp2b2+ Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
Allelic Composition: Atp2b2Obv/Atp2b2+ Genetic Background: C3HeB/FeJ-Atp2b2Obv
Allelic Composition: Atp2b2Deaf11/Atp2b2Deaf11 Genetic Background: BALB/c-Atp2b2Deaf11
Allelic Composition: Atp2b2Deaf11/Atp2b2+ Genetic Background: BALB/c-Atp2b2Deaf11
Allelic Composition: Atp2b2Deaf13/Atp2b2+ Genetic Background: BALB/c-Atp2b2Deaf13
Allelic Composition: Atp2b2Deaf13/Atp2b2Deaf13 Genetic Background: BALB/c-Atp2b2Deaf13
Allelic Composition: Atp2b2Deaf11/Atp2b2Deaf13 Genetic Background: BALB/c-Atp2b2Deaf11/Atp2b2Deaf13
Allelic Composition: Atp2b2Elfin/Atp2b2+ Genetic Background: involves: C3H/HeJ * C57BL/6J
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MP:0006358 | absent pinna reflex | "complete failure to respond to an auditory stimulus by a characteristic ear twitch" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2m1Mae/Atp2b2m1Mae,Ppargtm2Mae/Ppargtm2Mae Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Atp2b2Obv/Atp2b2+ Genetic Background: C3HeB/FeJ-Atp2b2Obv
Allelic Composition: Atp2b2Obv/Atp2b2Obv Genetic Background: C3HeB/FeJ-Atp2b2Obv
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MP:0006359 | absent startle reflex | "failure to respond to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Atp2b2m1Mae/Atp2b2m1Mae,Ppargtm2Mae/Ppargtm2Mae Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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MP:0008579 | abnormal Purkinje cell differentiation | "atypical production of or inability to produce the neurons located at the interface of the molecular and internal granule layers of the cerebellar cortex" [ISBN:0838580343 "Kandel ER, et al. Principles of Neural Science, 3rd edition"] |
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Allelic Composition: Atp2b2wri/Atp2b2wri Genetic Background: involves: BALB/cAnN
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MP:0010053 | decreased grip strength | "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"] |
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Allelic Composition: Atp2b2m1Mae/Atp2b2m1Mae,Ppargtm2Mae/Ppargtm2Mae Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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MP:0011966 | abnormal auditory brainstem response waveform shape | "any anomaly in the characteristic pattern of electrical activity recording of a series of vertex positive waves generated by neurons in the ascending auditory system, that can be recorded from scalp electrograms by using computer-averaged responses to short tone bursts" [MGI:csmith] |
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Allelic Composition: Atp2b2dfw/Atp2b2dfw Genetic Background: C3H/HeJ-Atp2b2dfw/J
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MP:0011967 | increased or absent threshold for auditory brainstem response | "increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith] |
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Allelic Composition: Atp2b2dfw/Atp2b2dfw Genetic Background: C3H/HeJ-Atp2b2dfw/J
Allelic Composition: Atp2b2dfw/Atp2b2+ Genetic Background: C3H/HeJ-Atp2b2dfw/J
Allelic Composition: Atp2b2dfw-2J/Atp2b2dfw-2J Genetic Background: CByJ.A-Atp2b2dfw-2J/J
Allelic Composition: Atp2b2dfw-2J/Atp2b2+ Genetic Background: CByJ.A-Atp2b2dfw-2J/J
Allelic Composition: Atp2b2wri/Atp2b2wri Genetic Background: involves: BALB/cAnN
Allelic Composition: Atp2b2tm1Ges/Atp2b2tm1Ges Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
Allelic Composition: Atp2b2tm1Ges/Atp2b2+ Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss
Allelic Composition: Atp2b2tm1Ges/Atp2b2+ Genetic Background: involves: 129/Sv * 129X1/SvJ * Black Swiss * C3H/HeJ
Allelic Composition: Atp2b2dfw-2J/Atp2b2+,Cdh23ahl/Cdh23ahl Genetic Background: involves: CAST/Ei * BALB/cByJ
Allelic Composition: Atp2b2dfw-2J/Atp2b2+,Cdh23ahl/Cdh23ahl Genetic Background: involves: BALB/cByJ * MOLF
Allelic Composition: Atp2b2Obv/Atp2b2+ Genetic Background: C3HeB/FeJ-Atp2b2Obv
Allelic Composition: Atp2b2Tmy/Atp2b2+ Genetic Background: involves: BALB/c * C3H/HeH
Allelic Composition: Atp2b2Tmy/Atp2b2Tmy Genetic Background: involves: BALB/c * C3H/HeH
Allelic Composition: Atp2b2Deaf11/Atp2b2Deaf11 Genetic Background: BALB/c-Atp2b2Deaf11
Allelic Composition: Atp2b2Deaf11/Atp2b2+ Genetic Background: BALB/c-Atp2b2Deaf11
Allelic Composition: Atp2b2Deaf13/Atp2b2+ Genetic Background: BALB/c-Atp2b2Deaf13
Allelic Composition: Atp2b2Deaf13/Atp2b2Deaf13 Genetic Background: BALB/c-Atp2b2Deaf13
Allelic Composition: Atp2b2Deaf11/Atp2b2Deaf13 Genetic Background: BALB/c-Atp2b2Deaf11/Atp2b2Deaf13
Allelic Composition: Atp2b2Elfin/Atp2b2Elfin Genetic Background: involves: C3H/HeJ * C57BL/6J
Allelic Composition: Atp2b2Elfin/Atp2b2+ Genetic Background: involves: C3H/HeJ * C57BL/6J
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MP:0011968 | decreased threshold for auditory brainstem response | "reduction in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system" [MGI:csmith] |
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Allelic Composition: Atp2b2dfw-i5/Atp2b2dfw-i5 Genetic Background: involves: C57BL/6J * CBA/CaJ * DBA/2J
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MP:0012490 | abnormal cochlear VIII nucleus morphology | "any structural anomaly of two paired brainstem nuclei, the dorsal cochlear nucleus and the ventral cochlear nucleus, that lie dorsal and ventral, respectively, to the inferior cerebellar peduncle at the rostral pole of the medulla; the cochlear nuclei receive input from the cochlear nerve and send projections to the inferior colliculus, the medial geniculate, and other forebrain structures" [MGI:csmith] |
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Allelic Composition: Atp2b2dfw/Atp2b2dfw Genetic Background: C3H/HeJ-Atp2b2dfw/J
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