ENSDARG00000063572


Danio rerio

Features
Gene ID: ENSDARG00000063572
  
Biological name :perp
  
Synonyms : perp / PERP, TP53 apoptosis effector
  
Possible biological names infered from orthology : p53 apoptosis effector related to PMP-22 / Q96FX8 / Q9JK95
  
Species: Danio rerio
  
Chr. number: 13
Strand: 1
Band:
Gene start: 1155536
Gene end: 1170695
  
Corresponding Affymetrix probe sets: Dr.17133.1.S1_at (Zebrafish Array)   Dr.24923.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000118851
NCBI entrez gene - 494479     See in Manteia.
RefSeq - NM_001256207
RefSeq Peptide - NP_001243136
swissprot - E9QHT9
ZFIN ID - ZDB-GENE-050104-1
Ensembl - ENSDARG00000063572
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PERP1ENSGALG00000027536Gallus gallus
 PERP2ENSGALG00000027207Gallus gallus
 PERPENSG00000112378Homo sapiens
 PerpENSMUSG00000019851Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6PFT6 / tmem47 / transmembrane protein 47 / Q9BQJ4* / Q9JJG6*ENSDARG0000005732228


Protein motifs (from Interpro)
Interpro ID Name
 IPR004031  PMP-22/EMP/MP20/Claudin superfamily
 IPR015664  P53-induced protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009411 response to UV IMP
 biological_processGO:0042981 regulation of apoptotic process IMP
 biological_processGO:1902262 apoptotic process involved in blood vessel morphogenesis IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
Formation of the cornified envelope


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000108 fin fin epithelial cell disorganized , abnormal
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 ZFA:0000135 notochord notochord apoptotic , abnormal
notochord degenerate , abnormal
notochord epithelial cell circular , abnormal
notochord epithelial cell disorganized , abnormal
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 ZFA:0000368 integument integument apoptotic , abnormal
integument epithelial cell circular , abnormal
integument epithelial cell disorganized , abnormal
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 ZFA:0001058 caudal fin caudal fin collapsed , abnormal
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 ZFA:0001069 ventral fin fold ventral fin fold cell circular , abnormal
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 ZFA:0001094 whole organism whole organism decreased length , abnormal
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 ZFA:0001115 trunk trunk integument rough , abnormal
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 ZFA:0001117 post-vent region post-vent region decreased length , abnormal
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 ZFA:0001161 pectoral fin pectoral fin decreased length , abnormal
pectoral fin apoptotic , abnormal
pectoral fin malformed , abnormal
Show

 ZFA:0009065 endothelial cell endothelial cell apoptotic process increased occurrence , ameliorated
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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