ENSDARG00000068460


Danio rerio

Features
Gene ID: ENSDARG00000068460
  
Biological name :otog
  
Synonyms : otog / otogelin
  
Possible biological names infered from orthology : Q6ZRI0
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 39463050
Gene end: 39537292
  
Corresponding Affymetrix probe sets: Dr.7234.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000142662
Ensembl peptide - ENSDARP00000142739
swissprot - A0A1D5NS53
swissprot - A0A1D5NSC6
ZFIN ID - ZDB-GENE-120228-1
Ensembl - ENSDARG00000068460
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 OTOGENSGALG00000006208Gallus gallus
 OTOGENSG00000188162Homo sapiens
 OtogENSMUSG00000009487Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
otogl / otogelin-like / F7A4A7* / Q3ZCN5* / Otogelin-like protein *ENSDARG0000008875035
muc5.1 / mucin 5.1, oligomeric mucus/gel-forming / MUC5B* / MUC5AC* / P98088* / Q9HC84* / mucin 5B, oligomeric mucus/gel-forming* / mucin 5AC, oligomeric mucus/gel-forming*ENSDARG0000007033122
muc5.3 / mucin 5.3 / MUC5B* / MUC5AC* / P98088* / Q9HC84* / mucin 5B, oligomeric mucus/gel-forming* / mucin 5AC, oligomeric mucus/gel-forming*ENSDARG0000009947021
muc5.2 / mucin 5.2 / MUC5B* / MUC5AC* / P98088* / Q9HC84* / mucin 5B, oligomeric mucus/gel-forming* / mucin 5AC, oligomeric mucus/gel-forming*ENSDARG0000005855621
vwf / von Willebrand factor / P04275*ENSDARG0000007723119
scospondin / subcommissural organ spondin / SSPO* / Q8CG65* / SCO-spondin*ENSDARG0000006785916
zanl / zonadhesin, like / ZAN* / zonadhesin* / zonadhesin (gene/pseudogene)*ENSDARG0000005678113
si:ch211-39f2.3ENSDARG0000009753913
CABZ01080550.1ENSDARG0000010062113
si:dkey-65b12.6 / FCGBP* / 9530053A07Rik* / RIKEN cDNA 9530053A07 gene* / Fc fragment of IgG binding protein*ENSDARG0000007683012
tecta / tectorin alpha / O08523* / O75443*ENSDARG0000005955811
si:dkey-239b22.1ENSDARG0000003158810


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR001007  VWFC domain
 IPR001846  von Willebrand factor, type D domain
 IPR002919  Trypsin Inhibitor-like, cysteine rich domain
 IPR006207  Cystine knot, C-terminal
 IPR007934  Alpha-L-arabinofuranosidase B, arabinose-binding domain
 IPR014853  Uncharacterised domain, cysteine-rich
 IPR029034  Cystine-knot cytokine
 IPR030105  Otogelin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007605 sensory perception of sound IEA
 biological_processGO:0008344 adult locomotory behavior IEA
 biological_processGO:0032475 otolith formation IMP
 biological_processGO:0035889 otolith tethering IGI
 biological_processGO:0046373 L-arabinose metabolic process IEA
 biological_processGO:0048840 otolith development IMP
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0046556 alpha-L-arabinofuranosidase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000051 otic vesicle otic vesicle has fewer parts of type otolith , abnormal
otic vesicle otolith tethering delayed , abnormal
otic vesicle otolith formation delayed , abnormal
otic vesicle otolith tethering arrested , abnormal
Show

 ZFA:0000217 inner ear inner ear has fewer parts of type otolith , abnormal
inner ear quality , abnormal
Show

 ZFA:0000282 sensory system sensory system quality , abnormal
Show

 ZFA:0000530 lapillus lapillus absent , abnormal
Show

 ZFA:0000700 utricle utricle lacks all parts of type lapillus , abnormal
utricle otolith formation arrested , abnormal
utricle has fewer parts of type lapillus , abnormal
utricle otolith formation delayed , abnormal
Show

 ZFA:0001094 whole organism whole organism balance , abnormal
whole organism circling , abnormal
Show

 ZFA:0001617 otolith otolith quality , abnormal
otolith increased size , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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