ENSDARG00000068732


Danio rerio

Features
Gene ID: ENSDARG00000068732
  
Biological name :spry4
  
Synonyms : sprouty homolog 4 (Drosophila) / spry4
  
Possible biological names infered from orthology : 4 / Q9C004 / Q9WTP2 / sprouty RTK signaling antagonist 4
  
Species: Danio rerio
  
Chr. number: 21
Strand: 1
Band:
Gene start: 44684577
Gene end: 44691068
  
Corresponding Affymetrix probe sets: Dr.12410.1.S1_at (Zebrafish Array)   Dr.18614.1.A1_at (Zebrafish Array)   NM_131826_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000090302
NCBI entrez gene - 114437     See in Manteia.
RefSeq - NM_131826
RefSeq - XM_021468746
RefSeq Peptide - NP_571901
swissprot - F1QZW4
ZFIN ID - ZDB-GENE-010803-2
Ensembl - ENSDARG00000068732
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SPRY4ENSGALG00000033012Gallus gallus
 SPRY4ENSG00000187678Homo sapiens
 4 ENSMUSG00000024427Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
spry2 / sprouty RTK signaling antagonist 2 / O43597* / Q9QXV8*ENSDARG0000007830832
spry1 / sprouty homolog 1, antagonist of FGF signaling (Drosophila) / O43609* / sprouty RTK signaling antagonist 1*ENSDARG0000010398530


Protein motifs (from Interpro)
Interpro ID Name
 IPR007875  Sprouty
 IPR030790  Protein sprouty homologue 4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0009966 regulation of signal transduction IEA
 biological_processGO:0021594 rhombomere formation IMP
 biological_processGO:0030097 hemopoiesis IMP
 biological_processGO:0040036 regulation of fibroblast growth factor receptor signaling pathway IMP
 biological_processGO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway IMP
 biological_processGO:0048741 skeletal muscle fiber development IMP
 biological_processGO:0070373 negative regulation of ERK1 and ERK2 cascade IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000132 neural plate neural plate decreased length , abnormal
neural plate increased width , abnormal
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 ZFA:0000186 common cardinal vein common cardinal vein morphology , abnormal
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 ZFA:0000823 rhombomere 5 rhombomere 5 physical object quality , abnormal
rhombomere 5 increased area , abnormal
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 ZFA:0000948 rhombomere 3 rhombomere 3 fused with rhombomere 5 , abnormal
rhombomere 3 increased area , abnormal
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 ZFA:0001032 rhombomere 4 rhombomere 4 decreased area , abnormal
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 ZFA:0001086 muscle pioneer muscle pioneer decreased amount , abnormal
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 ZFA:0001094 whole organism whole organism wholly dorsalized , abnormal
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 ZFA:0001114 head head apoptotic , abnormal
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 ZFA:0009044 blood cell blood cell decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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