ENSDARG00000068833


Danio rerio

Features
Gene ID: ENSDARG00000068833
  
Biological name :dclre1b
  
Synonyms : B0V2S2 / dclre1b / DNA cross-link repair 1B
  
Possible biological names infered from orthology : 5 exonuclease Apollo / Q8C7W7 / Q9H816
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 24107030
Gene end: 24113604
  
Corresponding Affymetrix probe sets: Dr.17981.1.A1_at (Zebrafish Array)   NM_001077283_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000149606
Ensembl peptide - ENSDARP00000090466
NCBI entrez gene - 768137     See in Manteia.
RefSeq - NM_001077283
RefSeq Peptide - NP_001070751
swissprot - B0V2S2
ZFIN ID - ZDB-GENE-061013-328
Ensembl - ENSDARG00000068833
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DCLRE1BENSGALG00000028626Gallus gallus
 Q9H816ENSG00000118655Homo sapiens
 Q8C7W7ENSMUSG00000027845Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q5RGE5 / dclre1c / DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae) / Q96SD1* / Q8K4J0* / Protein artemis * / DNA cross-link repair 1C*ENSDARG0000004570419
dclre1a / DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae) / Q6PJP8* / DNA cross-link repair 1A*ENSDARG0000009176811


Protein motifs (from Interpro)
Interpro ID Name
 IPR001279  Metallo-beta-lactamase
 IPR011084  DNA repair metallo-beta-lactamase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000075 cell cycle checkpoint ISS
 biological_processGO:0000723 telomere maintenance ISS
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006303 double-strand break repair via nonhomologous end joining IBA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0031627 telomeric loop formation ISS
 biological_processGO:0031848 protection from non-homologous end joining at telomere IBA
 biological_processGO:0031860 telomeric 3" overhang formation ISS
 biological_processGO:0036297 interstrand cross-link repair IBA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 cellular_componentGO:0000781 chromosome, telomeric region ISS
 cellular_componentGO:0000784 nuclear chromosome, telomeric region IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005813 centrosome ISS
 molecular_functionGO:0003684 damaged DNA binding IBA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004527 exonuclease activity IEA
 molecular_functionGO:0008409 5"-3" exonuclease activity ISS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0035312 5"-3" exodeoxyribonuclease activity IBA


Pathways (from Reactome)
Pathway description
Fanconi Anemia Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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