ENSDARG00000068934


Danio rerio

Features
Gene ID: ENSDARG00000068934
  
Biological name :cyp1b1
  
Synonyms : cyp1b1 / cytochrome P450, family 1, subfamily B, polypeptide 1
  
Possible biological names infered from orthology : Cytochrome P450 1B1 / cytochrome P450 family 1 subfamily B member 1 / Q16678 / Q64429
  
Species: Danio rerio
  
Chr. number: 13
Strand: 1
Band:
Gene start: 42011285
Gene end: 42018948
  
Corresponding Affymetrix probe sets: DrAffx.2.29.A1_at (Zebrafish Array)   DrAffx.2.29.S1_at (Zebrafish Array)   DrAffx.2.86.S1_at (Zebrafish Array)   NM_001045256_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000107132
Ensembl peptide - ENSDARP00000105704
NCBI entrez gene - 100150054     See in Manteia.
RefSeq - NM_001045256
RefSeq - NM_001145708
RefSeq Peptide - NP_001038721
RefSeq Peptide - NP_001139180
swissprot - B8JKD5
ZFIN ID - ZDB-GENE-030902-1
Ensembl - ENSDARG00000068934
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CYP1B1ENSGALG00000025822Gallus gallus
 CYP1B1ENSG00000138061Homo sapiens
 Cyp1b1ENSMUSG00000024087Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cyp1c2 / cytochrome P450, family 1, subfamily C, polypeptide 2ENSDARG0000010178947
cyp1a / cytochrome P450, family 1, subfamily A / P05177* / CYP1A1* / CYP1A2* / P00184* / P00186* / P04798* / Cytochrome P450 1A1 * / Cytochrome P450 1A2 * / cytochrome P450 family 1 subfami...ENSDARG0000009831538
cyp1d1 / cytochrome P450, family 1, subfamily D, polypeptide 1ENSDARG0000003556934
cyp17a2 / cytochrome P450, family 17, subfamily A, polypeptide 2ENSDARG0000005396629
cyp17a1 / cytochrome P450, family 17, subfamily A, polypeptide 1 / P05093* / P27786* / Steroid 17-alpha-hydroxylase/17,20 lyase * / cytochrome P450 family 17 subfamily A member 1*ENSDARG0000003356629
cyp2x9 / cytochrome P450, family 2, subfamily X, polypeptide 9ENSDARG0000007077528
cyp2x6 / cytochrome P450, family 2, subfamily X, polypeptide 6 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000007965327
cyp2aa4 / cytochrome P450, family 2, subfamily AA, polypeptide 4 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000009880327
cyp2x7 / cytochrome P450, family 2, subfamily X, polypeptide 7 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000004400227
cyp2x8 / cytochrome P450, family 2, subfamily X, polypeptide 8 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000004399727
cyp2aa2 / y cytochrome P450, family 2, subfamily AA, polypeptide 2 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000010481126
cyp2x10.2 / cytochrome P450, family 2, subfamily X, polypeptide 10.2 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000000650126
cyp2x10.2 / cytochrome P450, family 2, subfamily X, polypeptide 10.2 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000006828326
cyp2aa8 / cyp2aa9 / cytochrome P450, family 2, subfamily AA, polypeptide 8 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000010454026
cyp2aa1 / cytochrome P450, family 2, subfamily AA, polypeptide 1 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000009900326
cyp2aa11 / cytochrome P450, family 2, subfamily AA, polypeptide 11 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000010345626
cyp2aa11 / cyp2aa12 / cytochrome P450, family 2, subfamily AA, polypeptide 11 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000010280526
cyp2aa9 / cytochrome P450, family 2, subfamily AA, polypeptide 9 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000009889025
cyp21a2 / cytochrome P450, family 21, subfamily A, polypeptide 2 / P08686* / Cyp21a1* / cytochrome P450 family 21 subfamily A member 2*ENSDARG0000003755025
cyp2x12 / cytochrome P450, family 2, subfamily X, polypeptide 12 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000009209125


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002401  Cytochrome P450, E-class, group I
 IPR008066  Cytochrome P450, E-class, group I, CYP1
 IPR017972  Cytochrome P450, conserved site
 IPR032971  Cytochrome P450 1B1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004497 monooxygenase activity IBA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070330 aromatase activity IEA


Pathways (from Reactome)
Pathway description
Endogenous sterols
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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