ENSDARG00000033566


Danio rerio

Features
Gene ID: ENSDARG00000033566
  
Biological name :cyp17a1
  
Synonyms : cyp17a1 / cytochrome P450, family 17, subfamily A, polypeptide 1
  
Possible biological names infered from orthology : cytochrome P450 family 17 subfamily A member 1 / P05093 / P27786 / Steroid 17-alpha-hydroxylase/17,20 lyase
  
Species: Danio rerio
  
Chr. number: 13
Strand: -1
Band:
Gene start: 28601195
Gene end: 28610965
  
Corresponding Affymetrix probe sets: Dr.25390.1.A1_s_at (Zebrafish Array)   Dr.6650.1.S1_at (Zebrafish Array)   NM_212806_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000043155
NCBI entrez gene - 399692     See in Manteia.
RefSeq - NM_212806
RefSeq Peptide - NP_997971
swissprot - A2ATX9
ZFIN ID - ZDB-GENE-040213-2
Ensembl - ENSDARG00000033566
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CYP17A1ENSGALG00000008121Gallus gallus
 P05093ENSG00000148795Homo sapiens
 P27786ENSMUSG00000003555Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cyp17a2 / cytochrome P450, family 17, subfamily A, polypeptide 2ENSDARG0000005396649
cyp21a2 / cytochrome P450, family 21, subfamily A, polypeptide 2 / P08686* / Cyp21a1* / cytochrome P450 family 21 subfamily A member 2*ENSDARG0000003755034
cyp1c2 / cytochrome P450, family 1, subfamily C, polypeptide 2ENSDARG0000010178931
cyp1b1 / cytochrome P450, family 1, subfamily B, polypeptide 1 / Q16678* / Q64429* / Cytochrome P450 1B1 * / cytochrome P450 family 1 subfamily B member 1*ENSDARG0000006893430
cyp1d1 / cytochrome P450, family 1, subfamily D, polypeptide 1ENSDARG0000003556930
cyp1a / cytochrome P450, family 1, subfamily A / P05177* / CYP1A1* / CYP1A2* / P00184* / P00186* / P04798* / Cytochrome P450 1A1 * / Cytochrome P450 1A2 * / cytochrome P450 family 1 subfami...ENSDARG0000009831529
cyp2x9 / cytochrome P450, family 2, subfamily X, polypeptide 9ENSDARG0000007077527
cyp2x6 / cytochrome P450, family 2, subfamily X, polypeptide 6 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000007965327
cyp2x7 / cytochrome P450, family 2, subfamily X, polypeptide 7 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000004400227
cyp2x12 / cytochrome P450, family 2, subfamily X, polypeptide 12 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000006829027
cyp2x10.2 / cytochrome P450, family 2, subfamily X, polypeptide 10.2 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000000650127
cyp2x10.2 / cytochrome P450, family 2, subfamily X, polypeptide 10.2 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000006828327
cyp2x8 / cytochrome P450, family 2, subfamily X, polypeptide 8 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000004399726
cyp2x12 / cytochrome P450, family 2, subfamily X, polypeptide 12 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000009209126
cyp2aa8 / cyp2aa9 / cytochrome P450, family 2, subfamily AA, polypeptide 8 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000010454025
cyp2aa11 / cyp2aa12 / cytochrome P450, family 2, subfamily AA, polypeptide 11 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000010280525
cyp2aa1 / cytochrome P450, family 2, subfamily AA, polypeptide 1 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000009900324
cyp2aa4 / cytochrome P450, family 2, subfamily AA, polypeptide 4 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000009880324
cyp2aa11 / cytochrome P450, family 2, subfamily AA, polypeptide 11 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000010345624
cyp2aa3 / cytochrome P450, family 2, subfamily AA, polypeptide 3 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000010334724


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002401  Cytochrome P450, E-class, group I
 IPR017972  Cytochrome P450, conserved site
 IPR033282  Steroid 17-alpha-hydroxylase/17,20 lyase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006694 steroid biosynthetic process IEA
 biological_processGO:0007548 sex differentiation IEA
 biological_processGO:0042448 progesterone metabolic process IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:1903449 androst-4-ene-3,17-dione biosynthetic process IDA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0004508 steroid 17-alpha-monooxygenase activity IDA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity IDA
 molecular_functionGO:0047442 17-alpha-hydroxyprogesterone aldolase activity IDA


Pathways (from Reactome)
Pathway description
Androgen biosynthesis
Glucocorticoid biosynthesis
Endogenous sterols


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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