ENSGALG00000008121


Gallus gallus

Features
Gene ID: ENSGALG00000008121
  
Biological name :CYP17A1
  
Synonyms : CYP17A1 / steroid 17-alpha-hydroxylase/17,20 lyase precursor
  
Possible biological names infered from orthology : cytochrome P450 family 17 subfamily A member 1 / P05093 / P27786 / Steroid 17-alpha-hydroxylase/17,20 lyase
  
Species: Gallus gallus
  
Chr. number: 6
Strand: -1
Band:
Gene start: 23388033
Gene end: 23390555
  
Corresponding Affymetrix probe sets: Gga.834.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000053047
Ensembl peptide - ENSGALP00000032532
NCBI entrez gene - 425056     See in Manteia.
RefSeq - NM_001001901
RefSeq Peptide - NP_001001901
swissprot - F1NYI7
swissprot - A0A1D5PJQ1
Ensembl - ENSGALG00000008121
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cyp17a1ENSDARG00000033566Danio rerio
 P05093ENSG00000148795Homo sapiens
 P27786ENSMUSG00000003555Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CYP1A2 / cytochrome P450 1A5 / CYP1A1* / P00184* / P00186* / P04798* / P05177* / Cytochrome P450 1A2 * / Cytochrome P450 1A1 * / cytochrome P450 family 1 subfamily A member 1* / cytochrome...ENSGALG0000000132031
CYP1B1 / cytochrome P450 family 1 subfamily B member 1 / Q16678* / Q64429* / Cytochrome P450 1B1 *ENSGALG0000002582231
CYP1C1ENSGALG0000004075431
CYP1A1 / cytochrome P450 1A4 / P05177* / CYP1A2* / P00184* / P00186* / P04798* / Cytochrome P450 1A1 * / Cytochrome P450 1A2 * / cytochrome P450 family 1 subfamily A member 1* / cytochrome...ENSGALG0000000132530
CYP21A1 / steroid 21-hydroxylase precursor / P08686* / CYP21A2* / cytochrome P450 family 21 subfamily A member 2*ENSGALG0000003974229
CYP2AB5 / Gallus gallus cytochrome P450, family 2, subfamily AB, polypeptide 5 (CYP2AB5), mRNA. / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSGALG0000004525527
CYP2AB3 / Gallus gallus cytochrome P450, family 2, subfamily AB, polypeptide 3 (CYP2AB3), mRNA. / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSGALG0000004535127
CYP2AB2 / Gallus gallus cytochrome P450, family 2, subfamily AB, polypeptide 2 (CYP2AB2), mRNA. / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSGALG0000000817826
CYP2AB4 / Gallus gallus cytochrome P450, family 2, subfamily AB, polypeptide 4 (CYP2AB4), mRNA. / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSGALG0000000810526
CYP2AB1 / Gallus gallus cytochrome P450, family 2, subfamily AB, polypeptide 1 (CYP2AB1), mRNA. / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSGALG0000000828323


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002401  Cytochrome P450, E-class, group I
 IPR017972  Cytochrome P450, conserved site
 IPR033282  Steroid 17-alpha-hydroxylase/17,20 lyase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006694 steroid biosynthetic process IEA
 biological_processGO:0006704 glucocorticoid biosynthetic process IEA
 biological_processGO:0007548 sex differentiation IEA
 biological_processGO:0008202 steroid metabolic process IEA
 biological_processGO:0042446 hormone biosynthetic process IEA
 biological_processGO:0042448 progesterone metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0004508 steroid 17-alpha-monooxygenase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047442 17-alpha-hydroxyprogesterone aldolase activity IEA


Pathways (from Reactome)
Pathway description
Androgen biosynthesis
Glucocorticoid biosynthesis
Endogenous sterols


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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