ENSGALG00000025822


Gallus gallus

Features
Gene ID: ENSGALG00000025822
  
Biological name :CYP1B1
  
Synonyms : CYP1B1 / cytochrome P450 family 1 subfamily B member 1
  
Possible biological names infered from orthology : Cytochrome P450 1B1 / Q16678 / Q64429
  
Species: Gallus gallus
  
Chr. number: 3
Strand: -1
Band:
Gene start: 32004825
Gene end: 32007728
  
Corresponding Affymetrix probe sets: GgaAffx.6670.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000041426
Ensembl peptide - ENSGALP00000048510
NCBI entrez gene - 421466     See in Manteia.
RefSeq - XM_015283751
swissprot - A0A1D5P727
swissprot - R4GH89
Ensembl - ENSGALG00000025822
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cyp1b1ENSDARG00000068934Danio rerio
 CYP1B1ENSG00000138061Homo sapiens
 Cyp1b1ENSMUSG00000024087Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CYP1C1ENSGALG0000004075451
CYP1A2 / cytochrome P450 1A5 / CYP1A1* / P00184* / P00186* / P04798* / P05177* / Cytochrome P450 1A2 * / Cytochrome P450 1A1 * / cytochrome P450 family 1 subfamily A member 1* / cytochrome...ENSGALG0000000132036
CYP1A1 / cytochrome P450 1A4 / P05177* / CYP1A2* / P00184* / P00186* / P04798* / Cytochrome P450 1A1 * / Cytochrome P450 1A2 * / cytochrome P450 family 1 subfamily A member 1* / cytochrome...ENSGALG0000000132535
CYP17A1 / steroid 17-alpha-hydroxylase/17,20 lyase precursor / P05093* / P27786* / Steroid 17-alpha-hydroxylase/17,20 lyase * / cytochrome P450 family 17 subfamily A member 1*ENSGALG0000000812130
CYP2AB4 / Gallus gallus cytochrome P450, family 2, subfamily AB, polypeptide 4 (CYP2AB4), mRNA. / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSGALG0000000810527
CYP2AB2 / Gallus gallus cytochrome P450, family 2, subfamily AB, polypeptide 2 (CYP2AB2), mRNA. / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSGALG0000000817827
CYP2AB5 / Gallus gallus cytochrome P450, family 2, subfamily AB, polypeptide 5 (CYP2AB5), mRNA. / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSGALG0000004525527
CYP2AB3 / Gallus gallus cytochrome P450, family 2, subfamily AB, polypeptide 3 (CYP2AB3), mRNA. / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSGALG0000004535127
CYP2AB1 / Gallus gallus cytochrome P450, family 2, subfamily AB, polypeptide 1 (CYP2AB1), mRNA. / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSGALG0000000828324
CYP21A1 / steroid 21-hydroxylase precursor / P08686* / CYP21A2* / cytochrome P450 family 21 subfamily A member 2*ENSGALG0000003974223


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002401  Cytochrome P450, E-class, group I
 IPR017972  Cytochrome P450, conserved site
 IPR032971  Cytochrome P450 1B1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0002930 trabecular meshwork development IEA
 biological_processGO:0006725 cellular aromatic compound metabolic process IEA
 biological_processGO:0006805 xenobiotic metabolic process IEA
 biological_processGO:0006809 nitric oxide biosynthetic process IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0008202 steroid metabolic process IEA
 biological_processGO:0008210 estrogen metabolic process IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress IEA
 biological_processGO:0009404 toxin metabolic process IEA
 biological_processGO:0009636 response to toxic substance IEA
 biological_processGO:0010575 positive regulation of vascular endothelial growth factor production IEA
 biological_processGO:0019369 arachidonic acid metabolic process IEA
 biological_processGO:0030199 collagen fibril organization IEA
 biological_processGO:0030336 negative regulation of cell migration IEA
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:0033629 negative regulation of cell adhesion mediated by integrin IEA
 biological_processGO:0042572 retinol metabolic process IEA
 biological_processGO:0042574 retinal metabolic process IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043542 endothelial cell migration IEA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0046427 positive regulation of JAK-STAT cascade IEA
 biological_processGO:0046466 membrane lipid catabolic process IEA
 biological_processGO:0048514 blood vessel morphogenesis IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0061298 retina vasculature development in camera-type eye IEA
 biological_processGO:0061304 retinal blood vessel morphogenesis IEA
 biological_processGO:0070301 cellular response to hydrogen peroxide IEA
 biological_processGO:0071407 cellular response to organic cyclic compound IEA
 biological_processGO:0071603 endothelial cell-cell adhesion IEA
 biological_processGO:2000377 regulation of reactive oxygen species metabolic process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Endogenous sterols
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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