ENSDARG00000069926


Danio rerio

Features
Gene ID: ENSDARG00000069926
  
Biological name :hsd3b1
  
Synonyms : hsd3b1 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
  
Possible biological names infered from orthology : Gm10681 / Gm4450 / HSD3B2 / Hsd3b3 / Hsd3b4 / Hsd3b5 / Hsd3b6 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6 / O35469 / P14060 / P24815 / P26149 / P26150 / P26439 / predicted gene 10681 / Q61694 / Q61767
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 21194445
Gene end: 21200464
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000061320
NCBI entrez gene - 553532     See in Manteia.
swissprot - F1QSA2
ZFIN ID - ZDB-GENE-081105-30
Ensembl - ENSDARG00000069926
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HSD3B1ENSGALG00000037951Gallus gallus
 HSD3B1ENSG00000203857Homo sapiens
 HSD3B2ENSG00000203859Homo sapiens
 Gm4450ENSMUSG00000090817Mus musculus
 Hsd3b1ENSMUSG00000027871Mus musculus
 Hsd3b2ENSMUSG00000063730Mus musculus
 Hsd3b3ENSMUSG00000062410Mus musculus
 Hsd3b4ENSMUSG00000095143Mus musculus
 Hsd3b5ENSMUSG00000038092Mus musculus
 Hsd3b6ENSMUSG00000027869Mus musculus
 Q61767ENSMUSG00000095388Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
hsd3b2 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 / Hsd3b3* / Hsd3b4* / Hsd3b5* / Hsd3b6* / Q61767* / Gm4450* / HSD3B1* / O35469* / P14060* / P24815* / P...ENSDARG0000001974776
hsd3b7 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase / Q9EQC1* / Q9H2F3* / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7*ENSDARG0000003696636
A8DZE7 / sdr42e1 / short chain dehydrogenase/reductase family 42E, member 1 / Q8WUS8* / Q9D665*ENSDARG0000009883828
sdr42e2 / short chain dehydrogenase/reductase family 42E, member 2 / A6NKP2*ENSDARG0000005991427
nsdhl / NAD(P) dependent steroid dehydrogenase-like / Q15738* / Q9R1J0* / Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating *ENSDARG0000009931524


Protein motifs (from Interpro)
Interpro ID Name
 IPR002225  3-beta hydroxysteroid dehydrogenase/isomerase
 IPR016040  NAD(P)-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006694 steroid biosynthetic process IEA
 biological_processGO:0043473 pigmentation IMP
 biological_processGO:0055114 oxidation-reduction process IEA
 molecular_functionGO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity IDA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA


Pathways (from Reactome)
Pathway description
Androgen biosynthesis
Mineralocorticoid biosynthesis
Glucocorticoid biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism increased pigmentation , abnormal
Show

 ZFA:0009091 melanocyte melanocyte increased amount , abnormal
melanocyte dispersed , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000069926 hsd3b1 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 / Hsd3b3* / Hsd3b4* / Hsd3b5* / Hsd3b6* / Q61767* / Gm4450* / HSD3B2* / O35469* / P14060* / P24815* / P...  / complex






 

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