ENSGALG00000037951


Gallus gallus

Features
Gene ID: ENSGALG00000037951
  
Biological name :HSD3B1
  
Synonyms : HSD3B1 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
  
Possible biological names infered from orthology : Gm10681 / Gm4450 / HSD3B2 / Hsd3b3 / Hsd3b4 / Hsd3b5 / Hsd3b6 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6 / O35469 / P14060 / P24815 / P26149 / P26150 / P26439 / predicted gene 10681 / Q61694 / Q61767
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 78465927
Gene end: 78476335
  
Corresponding Affymetrix probe sets: Gga.596.1.S1_at (Chicken Array)   Gga.596.1.S2_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000051482
NCBI entrez gene - 396015     See in Manteia.
RefSeq - XM_015294370
RefSeq - NM_205118
RefSeq - XM_015294359
RefSeq - XM_015294362
RefSeq Peptide - NP_990449
swissprot - A0A1D5PFB9
Ensembl - ENSGALG00000037951
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hsd3b1ENSDARG00000069926Danio rerio
 hsd3b2ENSDARG00000019747Danio rerio
 HSD3B1ENSG00000203857Homo sapiens
 HSD3B2ENSG00000203859Homo sapiens
 Gm4450ENSMUSG00000090817Mus musculus
 Hsd3b1ENSMUSG00000027871Mus musculus
 Hsd3b2ENSMUSG00000063730Mus musculus
 Hsd3b3ENSMUSG00000062410Mus musculus
 Hsd3b4ENSMUSG00000095143Mus musculus
 Hsd3b5ENSMUSG00000038092Mus musculus
 Hsd3b6ENSMUSG00000027869Mus musculus
 Q61767ENSMUSG00000095388Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HSD3B7* / Q9EQC1* / Q9H2F3* / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7*ENSGALG0000004536633
SDR42E2 / A6NKP2* / Gm5737* / short chain dehydrogenase/reductase family 42E, member 2*ENSGALG0000000696428
SDR42E1 / short chain dehydrogenase/reductase family 42E, member 1 / Q8WUS8* / Q9D665*ENSGALG0000000545628
A6NKP2* / Gm5737* / SDR42E2* / short chain dehydrogenase/reductase family 42E, member 2*ENSGALG0000002681726
NSDHL / NAD(P) dependent steroid dehydrogenase-like / Q15738* / Q9R1J0* / Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating *ENSGALG0000000749326


Protein motifs (from Interpro)
Interpro ID Name
 IPR002225  3-beta hydroxysteroid dehydrogenase/isomerase
 IPR016040  NAD(P)-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006694 steroid biosynthetic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 molecular_functionGO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA


Pathways (from Reactome)
Pathway description
Androgen biosynthesis
Mineralocorticoid biosynthesis
Glucocorticoid biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000037951 HSD3B1 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 / Hsd3b3* / Hsd3b4* / Hsd3b5* / Hsd3b6* / Q61767* / Gm4450* / HSD3B2* / O35469* / P14060* / P24815* / ...  / complex






 

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