ENSMUSG00000027871


Mus musculus

Features
Gene ID: ENSMUSG00000027871
  
Biological name :Hsd3b1
  
Synonyms : Hsd3b1 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 / P24815
  
Possible biological names infered from orthology : HSD3B2 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 / P14060 / P26439
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: F2.2
Gene start: 98852194
Gene end: 98859794
  
Corresponding Affymetrix probe sets: 10500565 (MoGene1.0st)   1448453_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000029465
Ensembl peptide - ENSMUSP00000102630
NCBI entrez gene - 15492     See in Manteia.
MGI - MGI:96233
RefSeq - XM_006501036
RefSeq - NM_001304800
RefSeq - NM_008293
RefSeq Peptide - NP_032319
RefSeq Peptide - NP_001291729
swissprot - P24815
swissprot - Q3UI20
Ensembl - ENSMUSG00000027871
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hsd3b1ENSDARG00000069926Danio rerio
 hsd3b2ENSDARG00000019747Danio rerio
 HSD3B1ENSGALG00000037951Gallus gallus
 HSD3B1ENSG00000203857Homo sapiens
 HSD3B2ENSG00000203859Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P26149 / Hsd3b2 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 / P14060* / HSD3B1* / P26439* / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid del...ENSMUSG0000006373084
O35469 / Hsd3b6 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6 / P26439* / HSD3B1* / HSD3B2* / P14060* / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and s...ENSMUSG0000002786984
P26150 / Hsd3b3 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 / P26439* / HSD3B1* / HSD3B2* / P14060* / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and s...ENSMUSG0000006241083
Q61767 / Hsd3b4 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4 / HSD3B1* / P14060* / P26439* / HSD3B2* / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and s...ENSMUSG0000009514377
Q61767 / Gm10681 / predicted gene 10681 / HSD3B1* / P26439* / P14060* / HSD3B2* / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2* / hydroxy-delta-5-steroid deh...ENSMUSG0000009538877
Q61694 / Hsd3b5 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 / HSD3B1* / P14060* / P26439* / HSD3B2* / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and s...ENSMUSG0000003809274
Gm4450 / HSD3B2* / P26439* / HSD3B1* / P14060* / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1* / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid d...ENSMUSG0000009081739
Hsd3b7 / Q9EQC1 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 / Q9H2F3*ENSMUSG0000004228938
Q9D665 / Sdr42e1 / short chain dehydrogenase/reductase family 42E, member 1 / Q8WUS8*ENSMUSG0000003430829
Gm5737 / short chain dehydrogenase/reductase family 42E, member 2 / A6NKP2* / SDR42E2*ENSMUSG0000010939227
Nsdhl / Q9R1J0 / Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating / Q15738* / NAD(P) dependent steroid dehydrogenase-like*ENSMUSG0000003134925


Protein motifs (from Interpro)
Interpro ID Name
 IPR002225  3-beta hydroxysteroid dehydrogenase/isomerase
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006694 steroid biosynthetic process ISO
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031966 mitochondrial membrane IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity ISO
 molecular_functionGO:0004769 steroid delta-isomerase activity ISO
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0102294 cholesterol dehydrogenase activity IEA


Pathways (from Reactome)
Pathway description
Androgen biosynthesis
Mineralocorticoid biosynthesis
Glucocorticoid biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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